Periodontal therapy and low birth weight: preliminary results from an alternative methodologic strategy

Journal of Periodontology
Isaac S Gomes-FilhoLituânia F Miranda

Abstract

The purpose of this study is to present the use of a non-randomized experimental design with multiple controls, with emphasis on a historical control group, as an alternative methodologic resource for studies on the association between periodontal disease and prematurity/low birth weight. The sample consisted of 234 pregnant women: 54 in the Test Group (treatment of periodontal disease); 68 in Control Group I (without periodontal disease); and 112 in Control Group II (historical control group, with untreated periodontal disease). The diagnosis of periodontal disease was established by means of a complete clinical examination, using measurements of probing depth, gingival recession, clinical attachment loss, and bleeding index. The women in the Test Group were treated for periodontitis and followed-up with periodontal support therapy throughout their pregnancies. After delivery, they were reevaluated regarding their periodontal condition, and information on the newborn's birth weight was obtained. This was also done for Control Groups I and II. Descriptive analyses on the study variables were performed using the χ(2) and Fisher exact tests. Association measurements (relative risk) were obtained using a significance level of 5%. ...Continue Reading

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Citations

May 29, 2015·Acta Odontologica Scandinavica·Luise Maria SouzaMaria Isabel Pereira Vianna
Nov 15, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·María Matilde UsinAdela Sembaj
Dec 17, 2014·Periodontology 2000·Rui V OppermannCristiano Susin
Jul 6, 2015·International Journal of Pharmaceutics·Anna Kopytynska-KasperczykWojciech Prochwicz
Aug 10, 2020·BMC Pediatrics·Camilla da Cruz MartinsGraciete Oliveira Vieira

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