Periodontal treatment and glycaemic control in patients with diabetes and periodontitis: an umbrella review

Australian Dental Journal
J E BoteroA A Agudelo-Suarez

Abstract

Studies suggest that non-surgical periodontal treatment improves glycaemic control in patients with diabetes and periodontitis. The aim of this umbrella review is to summarize the effects of periodontal treatment on glycaemic control in patients with periodontitis and diabetes. A systematic review of systematic reviews with or without meta-analysis published between 1995 and 2015 was performed. Three independent reviewers assessed for article selection, quality and data extraction. Thirteen (13) systematic reviews/meta-analysis were included for qualitative synthesis. A reduction (0.23 to 1.03 percentage points) in the levels of HbA1c at 3 months after periodontal intervention was found. This reduction was statistically significant in 10/12 meta-analysis. One review with sufficiently large samples found a non-significant reduction (-0.014 percentage points; 95% CI -0.18 to 0.16; p = 0.87). Only three studies separated the use of adjunctive antibiotics and found a reduction of 0.36 percentage points but the difference was not statistically significant. Highly heterogeneous short-term studies with small sample size suggest that periodontal treatment could help improve glycaemic control at 3 months in patients with type 2 diabetes...Continue Reading

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Citations

May 28, 2016·Australian Dental Journal·P Mark Bartold
Dec 28, 2016·Journal of Oral Science·Zekeriya TaşdemirCem A Gürgan
Aug 11, 2017·Tissue Engineering. Part C, Methods·Karim M Fawzy El-Sayed, Christof E Dörfer
Dec 27, 2017·Journal of Clinical Periodontology·Phoebus N Madianos, Panagiotis A Koromantzos
Nov 14, 2019·International Endodontic Journal·V NagendrababuP M H Dummer
Dec 1, 2019·Oral Diseases·Pablo Varela-CentellesJuan M Seoane-Romero
Jul 5, 2018·International Journal of Molecular Sciences·Helene HolmerKlas Sjöberg
May 16, 2017·Journal of Clinical Periodontology·Josephine Solowiej-WedderburnMark Pennington
Jun 22, 2018·International Urology and Nephrology·Zekeriya TasdemirIsmail Kocyigit
Sep 15, 2019·Diabetes Research and Clinical Practice·Wenche S Borgnakke
Oct 26, 2020·BMJ Open Diabetes Research & Care·Kirsten P J SmitsOlivier Kalmus
Feb 22, 2021·International Dental Journal·Kostas KapellasLisa M Jamieson
Apr 4, 2021·International Journal of Environmental Research and Public Health·Prakash PoudelAjesh George

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