Periodontitis and multiple markers of cardiometabolic risk in the fourth decade: A cohort study

Community Dentistry and Oral Epidemiology
Dara M ShearerRichie Poulton

Abstract

To examine associations between periodontitis at ages 32 and 38 and a range of early cardiometabolic risk biomarkers at age 38. Periodontal probing depth and bleeding on probing data collected during the age-32 and age-38 assessments in the Dunedin Multidisciplinary Health and Development Study were used to quantify periodontal inflammatory load. Retinal microvascular abnormalities, endothelial dysfunction, and metabolic syndrome data were collected during the age-38 assessment. Regression models were used to examine associations between these cardiometabolic risk markers and (1) the inflammatory load at age 38 and (2) the change in inflammatory load between ages 32 and 38. Periodontal inflammatory load was recorded for 890 Study members at age 32, 891 at age 38, and 856 at both ages. Retinal vessel data were available for 922, endothelial dysfunction data for 909 and metabolic syndrome data for 905 at age 38. Neither the inflammatory load of periodontitis at 38 nor the changes in inflammatory load 32-38 were found to be associated with any of the three cardiometabolic risk markers. Periodontitis was not associated with markers of cardiometabolic risk at this relatively early stage in the life course. It is possible that any in...Continue Reading

References

May 24, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Salomon AmarJoseph A Vita
Jan 1, 1964·The Journal of the American Dental Association·J C GREENE, J R VERMILLION
Oct 17, 2003·Current Eye Research·Michael D KnudtsonBarbara E K Klein
Dec 8, 2004·Journal of the American College of Cardiology·Piero O BonettiAmir Lerman
Jun 25, 2005·Journal of Periodontology·Cristiano SusinJasim M Albandar
Jun 25, 2005·American Heart Journal·Gerald SeinostErnst Pilger
Oct 20, 2005·Current Opinion in Cardiology·Ulf Landmesser, Helmut Drexler
May 26, 2006·Investigative Ophthalmology & Visual Science·Tien Yin WongEyal Shahar
Jun 1, 2006·Journal of Periodontology·W Murray ThomsonJames D Beck
Feb 23, 2007·Journal of Dental Research·Y ShimazakiY Yamashita
Mar 3, 2007·The New England Journal of Medicine·Maurizio S TonettiJohn Deanfield
Mar 14, 2007·Circulation·John E DeanfieldTon J Rabelink
Apr 4, 2007·Circulation·Richard Kahn
Jun 19, 2007·European Journal of Internal Medicine·Arnon BlumEran Front
Sep 20, 2007·Journal of Clinical Periodontology·Luigi NibaliMaurizio S Tonetti
Aug 7, 2008·The Journal of Clinical Endocrinology and Metabolism·Francesco D'AiutoGeorgios Tsakos
Nov 5, 2008·Journal of Periodontology·Yousef KhaderNemeh Al-akour
Jan 28, 2009·Survey of Ophthalmology·Cong SunTien Y Wong
May 21, 2009·Journal of Public Health Dentistry·Toyoko MoritaMasao Maeno
Sep 17, 2009·Annals of Internal Medicine·Kevin McGeechanTien Y Wong
Oct 8, 2009·Circulation. Cardiovascular Imaging·Gerald LiewTien Y Wong
Jul 22, 2010·Journal of Dental Research·P TimonenP Ylöstalo
Oct 5, 2010·International Journal of Pediatric Obesity : IJPO : an Official Journal of the International Association for the Study of Obesity·Bamini GopinathPaul Mitchell
Nov 3, 2010·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Carol Yim-Lui CheungTien Yin Wong
Apr 22, 2011·Arteriosclerosis, Thrombosis, and Vascular Biology·Bamini GopinathPaul Mitchell
May 12, 2011·Journal of Hypertension·Carol Y CheungTien Y Wong
May 24, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Li-Ping ChenKuan-Yu Hung
Aug 4, 2011·Epidemiology·Johannes TextorSven Knüppel
Apr 20, 2012·Circulation·Peter B LockhartUNKNOWN American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Di
Aug 8, 2012·Circulation·Andreas J FlammerAmir Lerman
Aug 25, 2012·Ophthalmology·Chelsea E MyersBarbara E K Klein
May 3, 2013·Journal of Clinical Periodontology·Maurizio S TonettiUNKNOWN Working group 1 of the joint EFP/AAP workshop
May 3, 2013·Journal of Clinical Periodontology·Harvey A Schenkein, Bruno G Loos
Oct 12, 2013·Journal of Clinical Periodontology·Wijnand J TeeuwBruno G Loos

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Citations

Dec 21, 2019·Psychosomatic Medicine·Noha GomaaCarlos Quiñonez
Jan 2, 2020·Diabetology & Metabolic Syndrome·Juan Antonio Arreguin-CanoGladys León-Dorantes
Jul 3, 2021·Journal of Clinical Medicine·Cornelia Melinda Adi SantosoAttila Nagy

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