Abstract
To investigate the association between periodontitis and cognitive impairment in elderly Koreans. Cross-sectional study with age- and sex-matched case-control selection. The Yangpyeong cardiovascular cohort (YCC), a part of the Korean Genome Epidemiologic Study (KoGES), Yangpyeong, South Korea. Individuals with cognitive impairment (n = 65) and cognitively normal controls (n = 124) aged 60 and older from the YCC. Alveolar bone loss was assessed on dental panoramic radiographs to categorize the cumulative history of periodontitis (HOP) into three groups: normal, moderate periodontitis, severe periodontitis. The Mini-Mental State Examination (MMSE) was used to categorize participants as cognitively normal or cognitively impaired. Age- and sex-matched conditional logistic regression models were used for analysis. Confounders considered in the analysis were age, sex, drinking, smoking, exercise, total cholesterol, total protein, body mass index, fasting plasma glucose, intima-media thickness, hypertension medication, and depression. Participants with HOP were more likely to have cognitive impairment than those without (odds ratio = 2.14, 95% confidence interval = 1.04-4.41). The interaction effect of smoking and exercise on periodo...Continue Reading
References
Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Jan 5, 2002·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Jung H LeeJong I Woo
Mar 27, 2003·Journal of the American Geriatrics Society·Deborah E BarnesIra B Tager
Jul 9, 2003·Neurology·K YaffeT Harris
May 19, 2004·Archives of Neurology·Marianne J EngelhartMonique M B Breteler
Mar 24, 2005·Dementia and Geriatric Cognitive Disorders·K W KimJ I Woo
Dec 20, 2005·Lancet·Cleusa P FerriUNKNOWN Alzheimer's Disease International
Apr 25, 2007·Acta Odontologica Scandinavica·Anna-Maija Hannele SyrjäläMatti Knuuttila
May 31, 2007·Neurology·Z S TanS Seshadri
Jun 19, 2007·American Journal of Epidemiology·Kaarin J AnsteyRichard O'Kearney
Feb 5, 2008·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Dawn E AlleyTeresa E Seeman
Jul 18, 2008·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Angela R KamerMony J de Leon
Feb 3, 2009·Neuropsychiatric Disease and Treatment·Amber WattsMargaret Gatz
May 8, 2009·Journal of Neurology, Neurosurgery, and Psychiatry·J M NobleC B Wright
Sep 10, 2009·Neurology·C HolmesV H Perry
Apr 20, 2010·Journal of the American Geriatrics Society·Elizabeth Krall KayeRaul I Garcia
May 22, 2010·The British Journal of Nutrition·Yoon Jung YangMi Kyung Kim
Jul 8, 2010·Gerodontology·Anna-Maija Hannele SyrjäläMatti Knuuttila
Jul 9, 2010·Journal of the American Geriatrics Society·Laura E MiddletonKristine Yaffe
Dec 24, 2010·Journal of Alzheimer's Disease : JAD·Ki Woong KimMaeng Je Cho
Jan 22, 2011·Dementia and Geriatric Cognitive Disorders·Julian N TrollorPerminder Sachdev
Aug 30, 2011·Journal of Periodontology·Dong-Hun HanHyun-Duck Kim
Mar 17, 2012·Journal of Periodontology·Paul I EkeRobert J Genco
May 2, 2012·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Pamela Sparks SteinDolph Dawson
May 3, 2013·Journal of Periodontology·Gerard J LindenFrank A Scannapieco
Jul 23, 2013·Journal of Dental Research·S NaorungrojG Heiss
Citations
Jan 10, 2018·Frontiers in Aging Neuroscience·Chris J CarterSim K Singhrao
Oct 23, 2018·Journal of Periodontal Research·Masanori IwasakiKozo Matsubayashi
Feb 20, 2018·BMC Geriatrics·Bumjo OhJi Won Yoo
May 10, 2020·Periodontology 2000·Angela R KamerMony J de Leon
Sep 30, 2017·Frontiers in Physiology·Jaya KumarPasuk Mahakknaukrauh
Aug 22, 2018·BMC Oral Health·Sho SaitoYoshinori Hattori
Jun 24, 2018·Clinical Oral Investigations·Alejandra MaldonadoSigrun Eick
Mar 26, 2021·Journal of Molecular Neuroscience : MN·Xinyi SuHongkun Wu
Apr 16, 2021·BMC Geriatrics·Minh-Tung DoHyun-Duck Kim
Jun 3, 2021·Journal of Clinical Medicine·Yoshihisa FujinamiYasuhiro Kuroda
Jul 3, 2021·International Journal of Environmental Research and Public Health·Haiying GuoMinquan Du
Jul 12, 2021·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Xin HuZhaonan Liu
Sep 1, 2021·Periodontology 2000·Mark I Ryder, Pinelopi Xenoudi