PMID: 9433995Jan 20, 1998Paper

Perioperative assessment of respiratory compliance and lung volume in infants with congenital diaphragmatic hernia: prediction of outcome

Journal of Pediatric Surgery
V KavvadiaK H Nicolaides

Abstract

Infants who have congenital diaphragmatic hernia (CDH) have high mortality and morbidity. The aim of this study was to determine the relative ability of the results of serial measurements of compliance of the respiratory system (CRS) and lung volume (functional residual capacity (FRC)) to predict poor outcome: death or oxygen dependency at 28 days. In addition, the authors wished to document the evolution of any lung function abnormalities during the perioperative period. Daily measurements of CRS and FRC were made in the first week of life and subsequently during week 2 in 16 infants who had a median gestational age of 38 weeks and birth weight of 3.2 kg. Seven infants had a poor outcome: five died and two others remained oxygen dependent beyond 28 days. The infants who had a poor outcome were characterized on day 1 by a significantly lower CRS, but not FRC (P < .05). In comparison with results from day 1, the median CRS of the infants overall had significantly improved only by week 2 (P < .05), there was no such significant change in FRC with increasing postnatal age. At week 2, only the CRS results differed significantly between those infants who had and who did not have poor outcome (P < .05). The results of serial measurem...Continue Reading

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Citations

Oct 12, 2000·Indian Journal of Pediatrics·M AroraT R Prasad
Feb 28, 2013·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E DonéJ Deprest
Oct 30, 2009·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M CannieJ Deprest
Mar 15, 2002·Anesthesiology Clinics of North America·Gregory B Hammer
Feb 12, 2002·Revista do Hospital das Clínicas·U Tannuri
Aug 30, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·A RomitiL Caforio
Apr 17, 2007·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Roberta L Keller
Sep 6, 2000·Pediatric Pulmonology·M W Beresford, N J Shaw
May 29, 2001·Anesthesia and Analgesia·G B Hammer

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