Aug 15, 2014

Perioperative atrial fibrillation and the long-term risk of ischemic stroke

JAMA : the Journal of the American Medical Association
Gino GialdiniHooman Kamel


Clinically apparent atrial fibrillation increases the risk of ischemic stroke. In contrast, perioperative atrial fibrillation may be viewed as a transient response to physiological stress, and the long-term risk of stroke after perioperative atrial fibrillation is unclear. To examine the association between perioperative atrial fibrillation and the long-term risk of stroke. Retrospective cohort study using administrative claims data on patients hospitalized for surgery (as defined by surgical diagnosis related group codes), and discharged alive and free of documented cerebrovascular disease or preexisting atrial fibrillation from nonfederal California acute care hospitals between 2007 and 2011. Patients undergoing cardiac vs other types of surgery were analyzed separately. Previously validated diagnosis codes were used to identify ischemic strokes after discharge from the index hospitalization for surgery. The primary predictor variable was atrial fibrillation newly diagnosed during the index hospitalization, as defined by previously validated present-on-admission codes. Patients were censored at postdischarge emergency department encounters or hospitalizations with a recorded diagnosis of atrial fibrillation. Of 1,729,360 elig...Continue Reading

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Mentioned in this Paper

Ischemic Cerebrovascular Accident
Perioperative Period
Physiological Stress
Episodic Ataxia Type 1
Kaplan-Meier Estimate
Blood Vessel
Chronic Disease

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