Perioperative beta-blocker therapy in vascular surgery: clinical update

Journal of Vascular Surgery
Daniel G Hackam

Abstract

Patients undergoing vascular surgery comprise a group at elevated risk of fatal and nonfatal perioperative cardiovascular events. In four recent longitudinal studies, the 30-day incidence of death in such patients was 3% to 6%, and the incidence of myocardial infarction was 5% to 14%. Growing evidence suggests that beta-adrenergic receptor antagonists prevent cardiovascular morbidity and mortality in high-risk patients undergoing noncardiac surgery, including those undergoing vascular surgery. This article reviews the available evidence concerning beta-blockers and provides guidance for their use in the perioperative setting.

References

Jul 24, 2001·European Heart Journal·D PoldermansUNKNOWN Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group
Dec 31, 2004·The New England Journal of Medicine·Edward O McFallsWilliam G Henderson
May 4, 2005·The Journal of Thoracic and Cardiovascular Surgery·Artyom SedrakyanJan van der Meulen
Jul 29, 2005·The New England Journal of Medicine·Peter K LindenauerEvan M Benjamin
Oct 8, 2005·BMJ : British Medical Journal·Donald RedelmeierAlexander Kopp

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