Surgical revascularization for adults with moyamoya disease (MD) includes direct, indirect, or combination bypasses. It is unclear which provides the best outcomes. We sought to determine the best surgical management for adults with MD by comparing perioperative complications and long-term outcomes among 3 bypass types. Literature databases were searched for articles reporting revascularization bypass outcomes for adults with MD. A pooled analysis of all qualified studies and meta-analysis using only studies reporting direct comparisons of 2 bypass types were performed. Overall odds ratios (ORs) comparing 2 bypass types were computed and publication bias was assessed. Rates of perioperative and long-term hemorrhage and ischemia and favorable outcomes were compared. Forty-seven studies were analyzed; 8 had level 1 or 2 evidence. Pooled analyses showed that perioperative hemorrhage rates were significantly (P = 0.02) lower with indirect compared with direct (OR, 0.03; 95% confidence interval [CI], 0.002-0.55) or combined (OR, 0.03; 95% CI, 0.002-0.53) bypasses. Meta-analysis showed that direct bypass was better at preventing long-term hemorrhage than was indirect bypass (OR, 0.26; 95% CI, 0.09-0.79; P = 0.02). Pooled analyses sho...Continue Reading
Effects of encephalo-duro-arterio-synangiosis on childhood moyamoya patients--swift disappearance of ischemic attacks and maintenance of mental capacity
Moyamoya disease in children and its surgical treatment. Introduction of a new surgical procedure and its follow-up angiograms
Surgical therapy for adult moyamoya disease. Can surgical revascularization prevent the recurrence of intracerebral hemorrhage?
Combined encephalo-arterio-synangiosis and encephalo-myo-synangiosis in the treatment of moyamoya disease
Effectiveness of superficial temporal artery-middle cerebral artery anastomosis in adult moyamoya disease: cerebral hemodynamics and clinical course in ischemic and hemorrhagic varieties
Cerebral revascularization using muscle free flap for ischemic cerebrovascular disease in adult patients
Efficacy of direct revascularization in adult Moyamoya disease: haemodynamic evaluation by positron emission tomography
Clinical course, surgical management, and long-term outcome of moyamoya patients with rebleeding after an episode of intracerebral hemorrhage: An extensive follow-Up study
Effect of direct arterial bypass on the prevention of future stroke in patients with the hemorrhagic variety of moyamoya disease
Moyamoya disease and Moyamoya syndrome: experience in Europe; choice of revascularisation procedures
Long-term outcome in children with moyamoya syndrome after cranial revascularization by pial synangiosis
Simultaneous superficial temporal artery to middle cerebral or anterior cerebral artery bypass with pan-synangiosis for Moyamoya disease covering both anterior and middle cerebral artery territories
Health-related quality of life (HRQOL) in older people practicing Tai Chi--comparison of the HRQOL with the national standards for age-matched controls
Cerebral ischemia due to compression of the brain by ossified and hypertrophied muscle used for encephalomyosynangiosis in childhood moyamoya disease
Long-term outcome of superficial temporal artery-middle cerebral artery bypass for patients with moyamoya disease in the US
Delayed intracerebral hemorrhage after superficial temporal artery-middle cerebral artery anastomosis in a patient with moyamoya disease: possible involvement of cerebral hyperperfusion and increased vascular permeability
Risk of intraoperative ischemia due to temporary vessel occlusion during standard extracranial-intracranial arterial bypass surgery
Age-dependent revascularization patterns in the treatment of moyamoya disease in a European patient population
Clinical features, surgical treatment, and long-term outcome in adult patients with moyamoya disease. Clinical article.
Novel bypass surgery for moyamoya disease using pericranial flap: its impacts on cerebral hemodynamics and long-term outcome
Successful superficial temporal artery-anterior cerebral artery direct bypass using a long graft for moyamoya disease: technical note
Outcome of repeat revascularization surgery for moyamoya disease after an unsuccessful indirect revascularization. Clinical article
Impact of extracranial-intracranial bypass on cerebrovascular reactivity and clinical outcome in patients with symptomatic moyamoya vasculopathy
Characterization of direct and indirect cerebral revascularization for the treatment of European patients with moyamoya disease
Long-term follow-up results in 142 adult patients with moyamoya disease according to management modality
Surgical treatment of moyamoya disease in adults: combined direct and indirect vs. indirect bypass surgery
Surgical outcomes for moyamoya angiopathy at barrow neurological institute with comparison of adult indirect encephaloduroarteriosynangiosis bypass, adult direct superficial temporal artery-to-middle cerebral artery bypass, and pediatric bypass: 154 revascularization surgeries in 140 affected hemispheres
Ischemic Stroke in Young Adults with Moyamoya Disease: Prognostic Factors for Stroke Recurrence and Functional Outcome after Revascularization
Complementary Relation Between Direct and Indirect Bypass in Progress of Collateral Circulation in Moyamoya Disease
Risk factors for and outcomes of postoperative complications in adult patients with moyamoya disease
Predictors of neoangiogenesis after indirect revascularization in moyamoya disease: a multicenter retrospective study
Risk factors for postoperative stroke in adults patients with moyamoya disease: a systematic review with meta-analysis
Quantitative Angiographic Hemodynamic Evaluation After Revascularization Surgery for Moyamoya Disease.
Time Course of Neoangiogenesis After Indirect Bypass Surgery for Moyamoya Disease : Comparison of Short-term and Long-term Follow-up Angiography.
Lessons Learned from the Initial Experience with Pedicled Temporoparietal Fascial Flap for Combined Revascularization In Moyamoya Angiopathy: A Case Series
Encephaloduroarteriosynangiosis with Dural Inversion for Moyamoya Disease in a Pediatric and Adult Population-a Single-Center 20-Year Experience.
2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association.
[Ischemic complications following surgical treatment of moyamoya disease: risk factors and prevention].
Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.
A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.
Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.