Perioperative complications and outcome after surgery for treatment of gastric carcinoma in dogs: A Veterinary Society of Surgical Oncology retrospective study of 40 cases (2004-2018)

Veterinary Surgery : VS
Brittany AbramsLaura E Selmic

Abstract

To describe the clinical characteristics, perioperative complications, and outcomes in dogs surgically treated for gastric carcinoma. Multi-institutional retrospective case series. Forty client-owned dogs with histologically confirmed gastric carcinoma. Medical records were reviewed for preoperative diagnostics, surgery, histopathology, postoperative complications, adjuvant chemotherapy, disease progression, and survival. Variables were assessed for associations with outcome by using Cox proportional hazards regression analysis. Surgical treatment included partial gastrectomy (28 dogs), Billroth I (9 dogs), subtotal gastrectomy (2 dogs), and submucosal resection (1 dog). Major postoperative complications occurred in 8 of 40 dogs, including septic peritonitis secondary to dehiscence in 4 dogs. The median progression free interval was 54 days, and the median survival time (MST) was 178 days (range, 1-1902). According to multivariable analysis results, experiencing an intraoperative complication was associated with an increased risk of death (hazard ratio [HR] 3.5, 95% CI 1.1-9.8, P = .005), and administration of adjuvant chemotherapy correlated with an improved survival (HR 0.4, 95% CI 0.2-0.9, P = .03). In this population of dog...Continue Reading

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Citations

Feb 11, 2021·Acta Veterinaria Scandinavica·Marcus Vinicius CândidoThomas Spillmann
Dec 18, 2020·The Journal of Veterinary Medical Science·Aki OhmiHajime Tsujimoto
May 15, 2021·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Melonie ZuercherAmandine Lejeune

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