Perioperative Considerations in the Management of Anticoagulation Therapy for Patients Undergoing Surgery

Current Pain and Headache Reports
Alice M KaiTrevor Banack

Abstract

As ambulatory surgery has become increasingly more common, the appropriate management of anticoagulation therapy in patients undergoing invasive procedures has become progressively more relevant to healthcare professionals. The purpose of this literature review is to provide an overview of current common anaticoagulants and their pharmacological properties and to evaluate recent relevant literature and bridging therapy and provide recommendations on risk-guided therapy. With the development of new drugs and the advancing study and practice of anticoagulation use, clinicians must keep up-to-date on the optimal management of patients requiring anticoagulation. NOACs and warfarin continue to be the mainstays of treatment, with varying timelines regarding when to hold administration of the different agents within the perioperative period. There are numerous factors that are considered in patients with multiple comorbidities including the risk for stroke on long-term anticoagulation and risk for thromboembolism, particularly in the perioperative setting when certain medication regimens may be altered and/or briefly held. There is ongoing investigation whether certain NOACs have more efficacy or greater safety profiles, depending on ...Continue Reading

References

Jul 15, 1998·Mayo Clinic Proceedings·D J TiedeH V Schaff
Apr 30, 2003·Archives of Internal Medicine·Andrew S Dunn, Alexander G G Turpie
Feb 26, 2008·Arteriosclerosis, Thrombosis, and Vascular Biology·Peter L Gross, Jeffrey I Weitz
Aug 22, 2008·Current Medical Research and Opinion·Dagmar KubitzaWolfgang Mueck
Aug 18, 2012·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Marta A Miyares, Kyle Davis
Mar 12, 2013·Blood·Felix SchieleTobias Litzenburger
Oct 22, 2013·American Journal of Surgery·Brian K YorkgitisJay E Dujon
Sep 19, 2015·Journal of the American College of Cardiology·Stephen J Rechenmacher, James C Fang
Dec 25, 2015·Singapore Medical Journal·Choon How How
May 21, 2017·Anesthesiology Clinics·Allyson LemayRichard D Urman
Mar 6, 2018·The Surgical Clinics of North America·Margaret SmithAndrea Obi
Mar 30, 2018·AORN Journal·Courtney Meredith Zukowski, Jared Peak
Apr 6, 2018·Geriatric Orthopaedic Surgery & Rehabilitation·Razvan TaranuWill Eardley

❮ Previous
Next ❯

Citations

May 18, 2020·Annals of Vascular Surgery·Lucero G ParedesJeffrey J Siracuse

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Transactions of the American Ophthalmological Society
Pouya N Dayani, M Gilbert Grand
Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Brent B Ward, Miller H Smith
Current Opinion in Anaesthesiology
Paul J Samuels, Matthew D Sjoblom
© 2022 Meta ULC. All rights reserved