Perioperative monitoring in high-risk infants after stage 1 palliation of univentricular congenital heart disease

The Journal of Thoracic and Cardiovascular Surgery
N S GhanayemJ S Tweddell

Abstract

Survival of high-risk patients with univentricular heart disease after Norwood palliation is reduced. We hypothesized that early goal-directed monitoring with venous oximetry and near-infrared spectroscopy would offset their increased vulnerability and improve survival. A prospective database of patients undergoing stage 1 palliation was used to assess differences in outcomes across risk groups in the setting of a comprehensive, goal-directed monitoring program. High-risk criteria included gestational age 35 weeks or less, birth weight less than 2.5 kg, and additional cardiac or extracardiac anomalies. Outcomes included survival to defined end points and measures of postoperative support. From September 2000 to September 2008, 162 patients underwent stage 1 palliation: 28% (45/162) high-risk and 72% (117/162) standard-risk patients. Lesions other than hypoplastic left heart syndrome were more common among high-risk patients (38%, 17/45, vs 15%, 18/117, P = .003). Operative survival was not statistically different(87%, 39/45, high risk vs 95%, 111/117, standard risk, P = .1). High-risk patients were more likely to receive inpatient treatment until stage 2 palliation (24%, 11/45, vs 10%, 12/117, P = .001) and had lower 1-year sur...Continue Reading

References

Apr 5, 2002·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Christian PizarroWilliam I Norwood
Jul 10, 2002·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·J William GaynorThomas L Spray
Aug 21, 2003·The Journal of Thoracic and Cardiovascular Surgery·Shunji SanoShin-ichi Ohtsuki
Oct 8, 2003·The Annals of Thoracic Surgery·William T MahleVincent K H Tam
Dec 11, 2003·The Journal of Thoracic and Cardiovascular Surgery·N S GhanayemJ S Tweddell
Mar 31, 2004·The Journal of Thoracic and Cardiovascular Surgery·Robert D B JaquissJames S Tweddell
Apr 28, 2004·The Annals of Thoracic Surgery·Anthony AzakieTom R Karl
Sep 15, 2004·Circulation·Nilto C De OliveiraGlen S Van Arsdell
Jan 26, 2006·The Journal of Thoracic and Cardiovascular Surgery·Chad N StasikRichard G Ohye
Jul 15, 2006·Cardiology in the Young·Christo I TchervenkovGiovanni Stellin
Sep 26, 2006·The Annals of Thoracic Surgery·John H ArtripFrançois Lacour-Gayet
Jan 30, 2007·The Journal of Thoracic and Cardiovascular Surgery·Jia LiGlen S Van Arsdell
Sep 25, 2007·The Annals of Thoracic Surgery·James S TweddellGeorge M Hoffman
Mar 22, 2008·The Annals of Thoracic Surgery·Christian PizarroWolfgang Radtke
Apr 30, 2008·The Annals of Thoracic Surgery·Jeffrey P JacobsJames A Quintessenza
Feb 3, 2009·Pediatric Cardiology·Gabe E OwensSonal T Owens

❮ Previous
Next ❯

Citations

Jun 15, 2011·Current Treatment Options in Cardiovascular Medicine·Vamsi V Yarlagadda, Melvin C Almodovar
Jan 6, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jan H HansenHans-Heiner Kramer
Oct 9, 2013·The Journal of Thoracic and Cardiovascular Surgery·Joshua M Friedland-LittleRanjit Aiyagari
Mar 29, 2014·The Journal of Thoracic and Cardiovascular Surgery·Nancy A RuddNancy S Ghanayem
Jun 17, 2011·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·S O AlgraF Haas
Jun 9, 2012·Journal of Perinatology : Official Journal of the California Perinatal Association·J J ParisM D Schreiber
Feb 4, 2014·The Annals of Thoracic Surgery·James S Tweddell
Jan 16, 2013·The Journal of Thoracic and Cardiovascular Surgery·George M HoffmanNancy S Ghanayem
Mar 30, 2011·Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual·Desmond Bohn
Jun 24, 2011·Congenital Heart Disease·Brady S MoffettChristopher J Petit
Mar 19, 2011·Paediatric Anaesthesia·Nicholette Kasman, Ken Brady
Nov 26, 2013·Paediatric Anaesthesia·John P Scott, George M Hoffman
Jan 4, 2012·Journal of the American College of Cardiology·Edward J HickeyBrian W McCrindle
Feb 22, 2012·The Journal of Thoracic and Cardiovascular Surgery·James S TweddellUNKNOWN Pediatric Heart Network Investigators
Jan 10, 2017·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Michael C SpaederMary T Donofrio
Feb 19, 2013·Seminars in Cardiothoracic and Vascular Anesthesia·Mark D Twite, Richard J Ing
Apr 25, 2018·Circulation·Bradley S MarinoUNKNOWN American Heart Association Congenital Cardiac Defects Committee of the Council on Cardiovascular Disease in the Young; Counc
May 27, 2014·Journal of Korean Academy of Nursing·Sang Wha KimChun Soo Park
Aug 9, 2017·Comprehensive Child and Adolescent Nursing·Annica Sjostrom-Strand, Karina Terp
Aug 5, 2016·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Sarah TabbuttNancy Ghanayem
Jul 24, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Shobha S NatarajanJonathan J Rome
Oct 29, 2015·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Aparna U HoskoteMichael W Broadhead
Jul 17, 2019·World Journal for Pediatric & Congenital Heart Surgery·Gananjay G SalveDavid S Winlaw
Jul 12, 2020·The Annals of Thoracic Surgery·George M HoffmanJames S Tweddell

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

The New England Journal of Medicine
Richard G OhyePediatric Heart Network Investigators
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
J William GaynorThomas L Spray
© 2021 Meta ULC. All rights reserved