Perioperative Outcomes of Minimally Invasive Esophagectomy Versus Open Esophagectomy: A Meta-Analysis of Randomized Controlled Trials.

Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
Muhammed A Memon, Rossita M Yunus

Abstract

To explore the perioperative outcomes, safety, and effectiveness of minimally invasive esophagectomy (MIE) versus open esophagectomy (OE). Randomized controlled comparing MIE versus OE were searched from PubMed and other electronic databases between January 1991 and March 2019. Thirteen outcome variables were analyzed. Random effects model was used to calculate the effect size. The meta-analysis was prepared in accordance with PRISMA guidelines. Four randomized controlled trials totaling 569 patients were analyzed. For MIE, there was a significantly reduction of 67% in the odds of pulmonary complications. For operating time, MIE was nonsignificantly 29 minutes longer. MIE was associated with nonsignificantly less blood loss of 443.98 mL. There was nonsignificant 60% reduction in the odds of total complications and 51% reduction in the odds of medical complications favoring MIE group. For delayed gastric emptying, there was a nonsignificant reduction of 75% in the odds ratio favoring the MIE group. For postoperative anastomotic leak, there was a nonsignificant increase of 48% in the odds ratio for MIE group. For gastric necrosis, chylothorax, reintervention and 30-day mortality, no difference was observed for both groups. There ...Continue Reading

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Citations

Mar 23, 2021·The Annals of Thoracic Surgery·Aaron M WilliamsRishindra M Reddy

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Methods Mentioned

BETA
surgical resection
dissection

Software Mentioned

metafor
MIOMIE
Cochrane
R
RAMIE
PRISMA
package

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