Perioperative SARS-CoV-2 infection among women undergoing major gynecologic cancer surgery in the COVID-19 era: A nationwide, cohort study from Turkey.

Gynecologic Oncology
Ali AyhanMehmet Mutlu Meydanli

Abstract

The objective of this study was to determine the rate of perioperative SARS-CoV-2 infection among gynecologic cancer patients undergoing major surgery. The database of the Turkish Ministry of Health was searched in order to identify all consecutive gynecologic cancer patients undergoing major surgery between March 11, 2020 and April 30, 2020 for this retrospective, nationwide, cohort study. The inclusion criteria were strictly founded on a final histopathological diagnosis of a malignant gynecologic tumor. COVID-19 cases were diagnosed by reverse transcriptase- polymerase chain reaction testing for SARS-CoV-2. The rate of perioperative SARS-CoV-2 infection and the 30-day mortality rate of COVID-19 patients were investigated. During the study period, 688 women with gynecologic cancer undergoing major surgery were identified nationwide. The median age of the patients was 59 years. Most of the surgeries were open (634/688, 92.2%). There were 410 (59.6%) women with endometrial cancer, 195 (28.3%) with ovarian cancer, 66 (9.6%) with cervical cancer, 14 (2.0%) with vulvar cancer and 3 (0.4%) with uterine sarcoma. The rate of SARS-CoV-2 infections confirmed within 7 days before or 30 days after surgery was 46/688 (6.7%). All but one w...Continue Reading

References

Sep 19, 2018·The Lancet. Respiratory Medicine·Eva KirmeierUNKNOWN POPULAR Contributors
Feb 19, 2020·The Lancet Oncology·Wenhua LiangJianxing He
Feb 29, 2020·The New England Journal of Medicine·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19
Mar 29, 2020·The European Respiratory Journal·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19
Mar 30, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Pedro T RamirezRene Pareja
Apr 1, 2020·Annals of Oncology : Official Journal of the European Society for Medical Oncology·L ZhangM Zhou
Apr 7, 2020·American Journal of Obstetrics and Gynecology·Emily E Weber LeBrunJohn C Smulian
Apr 14, 2020·JAMA : the Journal of the American Medical Association·Deborah SchragEthan Basch
Apr 29, 2020·Critical Reviews in Oncology/hematology·Elissar MoujaessMarwan Ghosn
May 13, 2020·The British Journal of Surgery·UNKNOWN Welsh Surgical Research Initiative (WSRI) Collaborative
May 15, 2020·Journal of Gynecology Obstetrics and Human Reproduction·Vincent LavouéPierre Collinet
May 27, 2020·International Journal of Surgery·Lucia MolettaMichele Valmasoni
Sep 26, 2020·Indian Journal of Gynecologic Oncology·Neerja Bhatla, Seema Singhal
Sep 29, 2020·Gynecologic Oncology·Melissa K FreyEloise Chapman-Davis

❮ Previous
Next ❯

Citations

Apr 17, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Ali AyhanCagatay Taskiran

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection

Software Mentioned

Statistical Package for Social Sciences ( SPSS )

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
Polat DursunAteş Karateke
Current Opinion in Oncology
F Lawton, R Smith
International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Rebecca LuckettSurbhi Grover
© 2021 Meta ULC. All rights reserved