Periorbital subcutaneous tumor-like lesion due to Dirofilaria repens

International Journal of Surgical Pathology
Albino EccherFabio Menestrina

Abstract

Dirofilariasis is a zoonotic infection, which is occasionally seen in humans and rarely found as a subcutaneous orbital swelling. The authors report a case of a 62-year-old woman presented with a 3-month history of a right periorbital subcutaneous nodule. Treatment with antibiotics and corticosteroids was not satisfactory. Magnetic resonance imaging analysis showed a nodule with a central colliquative area. The lesion displaced the eyeball superiorly but did not affect the intraorbital muscles. The patient was subjected to excisional biopsy and the nodule measured 15 mm. Histological findings showed microabscess reaction with heterogeneous lymphoid infiltration. Additional consecutive sections finally showed Dirofilaria repens, curled up in spirals with external cuticular ridges in an environment characterized by epithelioid cells. The lesion did not recur for 5 months. Periorbital swelling can be rarely caused by Dirofilaria repens; therefore, this diagnosis should be considered in all cases of subcutaneous inflammatory or tumor-like lesion of unknown etiology.

References

Dec 1, 1976·American Journal of Ophthalmology·D ThomasE Torczynski
Apr 1, 1991·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·O P Settnes, E Engebjerg
Apr 1, 1997·The American Journal of Tropical Medicine and Hygiene·T C OrihelJ Alger
Mar 23, 1999·Nursing Standard·S Conder
Aug 26, 1999·Parasitology Today·A MuroF Simón
Jan 13, 2000·American Journal of Rhinology·H BraunR Gröll
May 22, 2003·Orbit·Romesh I AngunawelaPaul Rosser
Mar 11, 2006·Orbit·S GorezisM Stefaniotou

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Citations

Apr 22, 2009·Journal of Helminthology·A M DzamićI F Kranjcić-Zec
Mar 23, 2011·Vector Borne and Zoonotic Diseases·Claudio GenchiFrancesco Rivasi
Jul 6, 2012·Clinical Microbiology Reviews·Fernando SimónJose Alberto Montoya-Alonso
Mar 25, 2011·Parasites & Vectors·Domenico Otranto, Mark L Eberhard
Apr 5, 2011·Journal of Tropical Medicine·Nicolas ArgyAhmed Abou-Bacar
Oct 3, 2018·European Journal of Ophthalmology·Andrea MonteselChiara Posarelli

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