Periovulatory follicular fluid hormone levels in spontaneous human cycles

The Journal of Clinical Endocrinology and Metabolism
M M SeibelL Levesque

Abstract

We measured follicular fluid hormone levels in 48 normally cycling infertile women who underwent follicle puncture and oocyte retrieval during diagnostic laparoscopy at time-bracketed intervals after an endogenous LH surge. Follicular fluid LH, FSH, PRL, estrone (E1), estradiol (E2), progesterone (P), androstenedione (A), and testosterone (T) concentrations and P/E2 and A/E2 ratios were determined. Oocytes were classified as germinal vesicle (gv), metaphase I (mI), metaphase II (mII), or degenerating (dg). Follicular fluid (ff) hormone levels then were correlated with the stage of oocyte maturation. There were no differences in ff E1 or E2 levels at any stage of oocyte maturation, except that the mean ff E2 concentration was significantly (P less than 0.05) lower in ff containing dg oocytes [2,474 +/- 1,435 (+/- SE) nmol/L] than in those containing the other oocyte stages. The mean P levels were significantly (P less than 0.0001) higher in ff containing mI (48,781 +/- 10,240 nmol/L) and mII (41,801 +/- 11,098 nmol/L) oocytes than in ff containing gv oocytes (1371 +/- 696 nmol/L). The mean A level was highest (P less than 0.01) in dg-associated ff. Similarly, T was highest (P less than 0.05) in ff containing dg (52 +/- 14 nmol/L...Continue Reading

Citations

Feb 1, 1989·Journal of in Vitro Fertilization and Embryo Transfer : IVF·M M Seibel, D M Smith
Apr 1, 1997·Journal of Assisted Reproduction and Genetics·K L DurinziS E Lanzendorf
Mar 2, 2002·Fertility and Sterility·Paul C LinSteven T Nakajima
Jan 14, 2003·Fertility and Sterility·John Y PhelpsHoward A Zacur
Mar 3, 2004·Reproductive Biomedicine Online·Ri-Cheng ChianSeang-Lin Tan
Feb 13, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M PoehlW Feichtinger
Apr 1, 1991·Journal of Endocrinological Investigation·C MannaR Canipari
Nov 2, 2004·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·L O B CostaM F Silva de Sá
Mar 3, 2018·Journal of Assisted Reproduction and Genetics·M G Da BroiP A Navarro
Feb 1, 1997·Endocrine Reviews·B C Fauser, A M Van Heusden
Sep 6, 2001·Diseases of the Colon and Rectum·J H Xing, E E Soffer
Sep 1, 1991·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·E ScheenjesJ Kremer
Dec 20, 2020·Molecular and Cellular Endocrinology·Rosalieke E WiegelA H Jan Danser
Apr 21, 2021·Molecular and Cellular Endocrinology·Rosalieke E WiegelA H Jan Danser
Jul 1, 1997·Frontiers in Neuroendocrinology·Y Yoshimura

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