Peripapillary Halo in Inflammatory Papillitis of Birdshot Chorioretinopathy.

Clinical Ophthalmology
Mohamed M KhodeiryRichard K Lee

Abstract

Peripapillary halos (PPH) are peripapillary changes observed surrounding the optic nerve head in normal eyes and eyes with different disorders. Recognizing the microstructure and mechanism of development of these halos will help clinicians understand the different associated retinal and optic nerve head pathologies. We describe the in vivo histological characteristics of PPH in birdshot chorioretinopathy (BSCR). This was a prospective observational case-series in a single tertiary referral center. Six eyes of three patients with PPH associated with BSCR were determined through clinical examination, fundus photography, and fundus autofluorescence (FAF). Patients underwent swept-source optical coherence tomography (SS-OCT) imaging of the optic nerve head and peripapillary region. In SS-OCT B-scans across the area of PPH, we observed thinning and interruption of retinal pigment epithelium (RPE)-Bruch's membrane complex. These halos are a circumferential form of alpha zone RPE-associated crescentic peripapillary atrophy (PPA), unlike the PPH observed with myopia and normal aging. PPH in BSCR patients may be a sign of prior inflammatory optic neuropathy.

References

Feb 1, 1992·Archives of Ophthalmology·J B JonasG O Naumann
Jan 1, 1988·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·E J Rockwood, D R Anderson
Dec 1, 1971·The British Journal of Ophthalmology·J Primrose
Aug 1, 1982·American Journal of Ophthalmology·R B NussenblattA E Maumenee
Jan 1, 1980·American Journal of Ophthalmology·S J Ryan, A E Maumenee
Nov 26, 2002·The British Journal of Ophthalmology·P A GaudioJ Brooks Crawford
May 4, 2004·Ophthalmology·Aniki RothovaG Seerp Baarsma
Jul 28, 2004·Investigative Ophthalmology & Visual Science·Jost B JonasWido M Budde
Mar 4, 2005·Current Opinion in Ophthalmology·Jost B Jonas
Jul 26, 2005·American Journal of Ophthalmology·Jennifer E ThorneJohn H Kempen
Nov 3, 2005·Survey of Ophthalmology·Kayur H ShahGary N Holland
Jan 3, 2006·American Journal of Ophthalmology·Ralph D LevinsonGary N Holland
May 16, 2006·Arquivos brasileiros de oftalmologia·Oswaldo Ferreira Moura BrasilHaroldo Vieira de Moraes
Oct 31, 2006·Ophthalmology·Liang XuJost B Jonas
Feb 24, 2009·American Journal of Ophthalmology·Richard F Spaide
Jul 22, 2011·Investigative Ophthalmology & Visual Science·Atsushi NonakaNagahisa Yoshimura
Nov 24, 2011·Ocular Immunology and Inflammation·Antoine P BrézinRalph D Levinson
Jan 21, 2012·Current Opinion in Ophthalmology·Gabriel T Chong, Richard K Lee
Oct 25, 2012·PloS One·Jost B JonasSonghomitra Panda-Jonas
Feb 23, 2013·Current Opinion in Ophthalmology·Mehreen Adhi, Jay S Duker
Apr 2, 2013·Survey of Ophthalmology·Hossein Nazari Khanamiri, Narsing A Rao
Nov 30, 2013·The British Journal of Ophthalmology·Sergio CopeteJosé M Ruiz-Moreno
Mar 25, 2016·Orphanet Journal of Rare Diseases·Marcelo Mendes LavezzoJoyce Hisae Yamamoto
Apr 14, 2016·Ocular Immunology and Inflammation·Sukhum Silpa-ArchaC Stephen Foster
May 28, 2016·Acta Ophthalmologica·Michel M TeussinkThomas Theelen
May 5, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Olga Garcia-GarciaJosep M Caminal-Mitjana
Sep 8, 2018·JAMA Ophthalmology·Lucas A TorresBalwantray C Chauhan
Mar 17, 2020·Investigative Ophthalmology & Visual Science·Hae Rang KimMin Hee Suh
Jan 1, 2019·Ophthalmology. Glaucoma·Isaiah J DaviesM Bruce Shields
Jan 1, 2018·Ophthalmology. Glaucoma·Mohamed S SayedRichard K Lee
Feb 2, 2021·Current Eye Research·Xiangxiang LiuNingli Wang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Obstetrics and Gynecology
Anna Sara ObergBrian T Bateman
The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Naama BuzagloEyal Sheiner
© 2021 Meta ULC. All rights reserved