Peripartum cardiomyopathy: A systematic review of the literature

Clinical Cardiology
Zain Ul Abideen AsadTarun W Dasari

Abstract

Peripartum cardiomyopathy (PPCM) is a rare cause of heart failure. It is defined as cardiomyopathy that develops in the last month of pregnancy or within 5 months of the postpartum period without an identifiable cause. We conducted a systematic review of literature of prospective studies with a focus on echocardiographic and long-term clinical outcomes in PPCM. We searched MEDLINE and Embase up to October 1, 2017. Prospective studies (sample size ≥20) reporting all-cause mortality and follow-up duration of ≥1 year were included. Of the 956 studies identified, 7 met the inclusion criteria. A total of 445 patients with a mean age of 30 years (range, 27-32 years) were included. The mean follow-up duration was 41 months (range, 12-61 months). The majority of patients had New York Heart Association class III or IV symptoms at the time of diagnosis. Only 3 studies reported data on ethnicity where the majority of patients were non-Caucasian. Most of the patients (81%-93%) were on guideline-directed medical therapy, except 1 study (41%). Left ventricular ejection fraction at baseline ranged from 24% to 35% (mean, 28%) and at follow-up from 31% to 53% (mean, 44%). Recovery in systolic function was noted in 20% to 82% (mean, 50%) of pati...Continue Reading

References

Dec 1, 1971·Circulation·J G DemakisR M Gunnar
Jun 4, 2005·Obstetrics and Gynecology·Jeff B ChapaJudith U Hibbard
Jun 13, 2006·The American Journal of Cardiology·Lisa M MielniczukDavid H Birnie
Aug 29, 2006·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·T K MishraS N Routray
Jul 17, 2007·The American Journal of Cardiology·Somjot S BrarAlbert Yuh-Jer Shen
Nov 28, 2008·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·James D FettVenkita Suresh
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Sep 16, 2009·International Journal of Cardiology·Karen SliwaDenise Hilfiker-Kleiner
Feb 23, 2010·Journal of the American College of Cardiology·Mindy B GentryGuy L Reed
Aug 3, 2010·European Journal of Heart Failure·Karen SliwaUNKNOWN Heart Failure Association of the European Society of Cardiology Working Group on Peripartum Cardiomyopathy
May 17, 2012·European Journal of Heart Failure·Murat BitekerBiykem Bozkurt
Aug 22, 2015·Journal of the American College of Cardiology·Dennis M McNamaraUNKNOWN IPAC Investigators
Sep 25, 2017·European Heart Journal·Mattia ArrigoAlexandre Mebazaa

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Citations

Mar 8, 2019·Clinical Cardiology·Michael C HonigbergUNKNOWN IPAC Investigators
Oct 28, 2019·The American Journal of Nursing·Marc-André Maheu-CadotteGuillaume Fontaine

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