Peripheral and Central Nervous System Involvement in Recently Diagnosed Cases of Hypothyroidism: An Electrophysiological Study

Annals of Medical and Health Sciences Research
N GuptaK S Arora

Abstract

Hypothyroidism, one of the most common endocrine disorders, may induce neurological abnormalities at an early stage of the disease. The study was designed to assess the electrophysiological alterations of some selected variables of nerve conduction, brainstem auditory evoked potentials (BAEPs), and visual evoked potentials (VEPs) in hypothyroid patients. Sixty patients of newly diagnosed hypothyroidism and an equal number of age-matched controls were selected for the study. Nerve conduction studies that included parameters as latencies, conduction velocities, and amplitude of motor nerves, i.e., median, ulnar, common peroneal, tibial nerve, and sensory nerves, i.e., median and sural nerves was performed in both hypothyroid patients and controls. Further, BAEPs and VEPs of all the patients were done. The data were compiled and statistically analyzed using Student's unpaired t-test to observe any electrophysiological alterations in hypothyroid patients as compared to healthy controls. On comparative evaluation, statistically significant increase in latency of median, ulnar, tibial, and sural nerves; decrease in conduction velocities of all the tested nerves and decrease in amplitude of median, tibial, and sural nerves was observe...Continue Reading

Citations

Apr 18, 2018·Neurourology and Urodynamics·Octavio Sánchez-GarcíaFrancisco Castelán
Jul 3, 2019·Scientific Reports·Sina HulkkonenJorma Ryhänen
Jun 14, 2019·Journal of Medical Case Reports·Matthias HepprichMatthias Johannes Betz
Aug 11, 2020·Journal of Basic and Clinical Physiology and Pharmacology·Md Anzar AlamShabnam Ansari
Jun 2, 2021·The Journal of Clinical Endocrinology and Metabolism·Nicole PrinzReinhard W Holl

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Methods Mentioned

BETA
hormone replacement therapy

Software Mentioned

Neurostim

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