PMID: 6163202Jan 1, 1980Paper

Peripheral and prostatic vein steroid concentrations in benign prostatic hypertrophy patients before and after removal of the adenoma

Scandinavian Journal of Urology and Nephrology
O LukkarinenR Vihko

Abstract

The concentrations of androgenic steroids and some of their precursors were determined in the prostatic and peripheral veins of 16 patients with benign prostatic hypertrophy (BPH). The same steroids were also measured in the peripheral vein after removal of the adenoma. The mean concentration of 5 alpha-dihydrotestosterone in prostatic vein (4.40 nmol/l +/- 0.37, mean +/- S.E.M.) was significantly higher than in peripheral vein (2.63 nmol/l +/- 0.30, mean +/- S.E.M.) indicating secretion of this steroid by the adenoma. We did not observe any correlation between the weight of the removed tissue and the secretion of 5 alpha-dihydrotestosterone. The concentrations of pregnenolone, progesterone, 17 alpha-hydroxyprogesterone, androstenedione, testosterone and androsterone were the same in the prostatic and peripheral veins. There were no changes in the concentrations of steroids measured before and 1 and 6 months after removal of the BPH adenoma. It therefore appears that the secretion of 5 alpha-dihydrotestosterone by the adenoma is insufficient to influence the circulating levels of this steroid.

References

Sep 1, 1976·The Journal of Clinical Endocrinology and Metabolism·J GellerG Niwayama
Dec 1, 1976·The Journal of Clinical Endocrinology and Metabolism·A Vermeulen, W De Sy
Aug 1, 1977·Clinical Endocrinology·G L HammondR Vihko
Nov 1, 1977·British Journal of Urology·R GhanadianE P O'Donoghue
Aug 1, 1978·Clinical Endocrinology·G L HammondR Vihko
Jul 1, 1977·The Journal of Clinical Endocrinology and Metabolism·G L HammondR Vihko
Oct 1, 1975·The Journal of Clinical Endocrinology and Metabolism·R HortonM Cosgrove
Oct 1, 1974·Acta Endocrinologica·J A MahoudeauH Bricaire

❮ Previous
Next ❯

Citations

Apr 12, 2011·International Journal of Radiation Oncology, Biology, Physics·Al V TairaKent E Wallner
Apr 10, 2007·Cancer Detection and Prevention·Yoshitaka SekineKazuhiro Suzuki
Apr 24, 2008·International Journal of Urology : Official Journal of the Japanese Urological Association·Takashi ImamotoTomohiko Ichikawa
Oct 2, 2002·Obstetrics and Gynecology Clinics of North America·Geoffrey L Hammond
Aug 21, 2015·Acta Clinica Belgica·Karel De CaesteckerWillem Oosterlinck
Jul 29, 1998·The Journal of Urology·L R MillerP C Walsh
Dec 1, 2010·Hormone Molecular Biology and Clinical Investigation·Jean Fiet, Frank Giton
Nov 7, 2003·The Journal of Clinical Endocrinology and Metabolism·Arno W F T TooriansDavid J Handelsman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.