Peripheral blood mononuclear leukocyte cyclic adenosine monophosphate specific phosphodiesterase activity in childhood atopic dermatitis

The British Journal of Dermatology
I H CoulsonC A Holden

Abstract

Significantly elevated activity of peripheral blood mononuclear cell cAMP specific phosphodiesterase (PDE) activity has been previously reported in adults with atopic dermatitis and in the cord blood of children born to atopic parents. We have been unable to confirm such a significant elevation in children with atopic dermatitis, and we have not found any correlation with dermatitis severity, age or total serum IgE.

References

May 1, 1993·Clinical and Experimental Dermatology·C A Holden
Jan 25, 2005·American Journal of Respiratory and Critical Care Medicine·Hui-Fang TangPeng Wang
Feb 14, 2006·Biochimica Et Biophysica Acta·Hui-Fang TangXiangdong Wang
Mar 1, 1990·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C A Holden
Sep 1, 1990·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H A Sampson

Citations

Sep 1, 1976·The Journal of Investigative Dermatology·C E ReedT P Lee
May 1, 1977·The Journal of Investigative Dermatology·C W ParkerA Z Eisen
Sep 1, 1986·The Journal of Investigative Dermatology·C A HoldenJ M Hanifin
Jan 1, 1986·The British Journal of Dermatology·V S NeildJ M Bland
Jan 1, 1983·Annual Review of Pharmacology and Toxicology·D LagunoffG Read

Related Concepts

Dermatitis, Atopic
Eczema
Immunoglobulin E
Asthma
Hay Fever
3',5'-Cyclic-Nucleotide Phosphodiesterase
Nongranular Leukocyte
Age Factors
Dermatitis
Eczema, Infantile

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