PMID: 1200677Aug 1, 1975Paper

Peripheral gangrene in hypernatraemic dehydration of infancy

Archives of Disease in Childhood
S C Comay, C D Karabus

Abstract

Gangrene of the extremities complicating diarrhoea and severe hypernatraemic dehydration occurred in 6 infants. This is a rare complication of gastroenteritis, and its association with hypernatraemia does not seem to have previously been emphasized. The increased blood viscosity resulting from serum hyperosmolarity may have been responsible for the gangrene, and studies in our patients suggested that disseminated intravascular coagulation was present. In addition to fluid and electrolyte replacement, the infants were treated with heparin with some recovery of the affected extremities.

References

Nov 16, 1972·The New England Journal of Medicine·L A Harker, S J Slichter
Jun 1, 1973·The Journal of Pediatrics·G P GrossH R McGaughey
Jul 1, 1973·Archives of Disease in Childhood·T F Mackintosh, C H Walker
Jul 1, 1974·Archives of Disease in Childhood·M KhalilM M Abdel-Hay
Jul 23, 1970·The New England Journal of Medicine·R Wells
Dec 1, 1968·Plastic and Reconstructive Surgery·S I ShehadiI A Dabbous
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Mar 1, 1965·American Journal of Surgery·J W SMITHH CONWAY

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Citations

Jul 1, 1987·European Journal of Pediatrics·H NazerM Mustafa
Jul 5, 2001·Pediatric Emergency Care·R H van AmerongenT J Gaeta
May 5, 2011·Indian Journal of Pediatrics·Shivani DograSurjit Singh
Jul 24, 2007·The Journal of Pediatrics·Gabriel J EscobarThomas B Newman
May 10, 2017·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Caroline Morin, Isabelle Chevalier

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