Peripheral microcirculatory hemodynamic changes in patients with myocardial ischemia

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Zehava Ovadia-BlechmanPierre Chouraqui

Abstract

Patients with coronary heart disease demonstrate changes in skin microcirculation and a decrease in cutaneous blood mass. The goal of this study was to assess the feasibility of diagnosing myocardial ischemia based on peripheral microcirculatory variables. The skin microcirculatory measurements were monitored using an LPT system comprising a Laser Doppler Flowmeter (LDF), a photoplethysmograph (PPG) and a transcutaneous oxygen tension device (tc-PO2). Concurrently, heart rate and blood pressure were monitored. Measurements were performed before and after exercise stress test. Subjects were divided into ischemic (20) and nonischemic (27) patients based on myocardial perfusion imaging (MPI). The results indicate differences in LPT variables between ischemic and nonischemic patients following exercise, while no differences in the central variable values were observed between the two groups. Peripheral microcirculatory variables may be useful for non-invasive assessment of myocardial ischemia. The system has clinical potential for sensitive and noninvasive monitoring of vital variables during medical procedures in clinics, as well as in home care for patients who suffer from ischemic cardiac diseases.

References

Nov 1, 1995·Journal of the American Academy of Dermatology·R I KellyP S Mortimer
May 5, 1998·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·M RoccaR Giardino
Oct 3, 2002·The American Journal of Cardiology·Ehtasham QureshiAlan Rozanski
Dec 31, 2002·Journal of the American College of Cardiology·Pierre ChouraquiJacob Sheffy
Jun 21, 2005·Journal of the American College of Cardiology·Daniel R WitteMichiel L Bots
Dec 19, 2006·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Prem SomanJeffrey T Kuvin
Oct 2, 2007·Physiological Measurement·Hsin HsiuYuh-Ying Lin Wang
Dec 16, 2010·Circulation·Priya Kohli, Martha Gulati
Jun 15, 2011·Physiology·Jaume PadillaM Harold Laughlin
Aug 8, 2012·Circulation·Andreas J FlammerAmir Lerman
Jul 18, 2014·Medical Devices : Evidence and Research·Meir NitzanRobert Koppel
May 27, 2015·Respiratory Physiology & Neurobiology·Zehava Ovadia-BlechmanDavid Castel

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Citations

Apr 21, 2016·Cardiovascular Diabetology·Nikolaos Östlund PapadogeorgosMajid Kalani
Nov 7, 2016·Medical Engineering & Physics·Zehava Ovadia-BlechmanVered Aharonson
Mar 30, 2017·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·T Y LongT L Yang
Mar 7, 2019·International Wound Journal·Lea Peko CohenAmit Gefen
Feb 18, 2020·Lasers in Surgery and Medicine·Lilach GavishZehava Ovadia-Blechman
May 14, 2020·Journal of Aging Research·Renata SzygułaGrażyna Sondel
Dec 20, 2019·Biomedical Optics Express·Rafael Y BrzezinskiOshrit Hoffer
Nov 6, 2020·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Nikolaos Östlund PapadogeorgosMajid Kalani
Sep 3, 2021·Scientific Reports·Rafael Y BrzezinskiOshrit Hoffer

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