Peripheral neuropathies due to systemic lupus erythematosus in China

Medicine
Wang XianbinZeng Xiaofeng

Abstract

This article aims to analyze the frequency and clinical characteristics of peripheral neuropathy (PN) in patients with systemic lupus erythematosus (SLE).A total of 4924 SLE patients admitted to the Peking Union Medical College Hospital, Beijing, China, from January 1995 to September 2013 were included in this retrospective analysis. The individuals designated as control patients were selected from the pool of SLE patients without PN using the systematic sampling method of 1:2 during the same time.The prevalence of SLE-associated PN (SLE-PN) in SLE patients was 1.5% (73/4924). Seventy-nine cases of PN affected 73 patients and 6 of these patients (8.2%) presented with 2 types of PN. Among the 7 types of PN, polyneuropathy was the most frequent and was diagnosed in 47 cases (59.5%); the remaining patients suffered from mononeuropathy (13.9%), cranial neuropathy (12.7%), myasthenia gravis (10.1%), autonomic neuropathy (2.5%), or acute inflammatory demyelinating polyradiculoneuropathy (1.3%). Five patients developed PN before the onset of SLE (3 out of 5 patients had myasthenia gravis). The most common PN-related symptoms were myasthenia and numbness (50.6%), followed by pain in affected regions (35.9%). PN symptoms were relieved i...Continue Reading

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Citations

Jan 12, 2019·Expert Review of Clinical Immunology·Jaqueline Cristina de AmorimSimone Appenzeller
Nov 28, 2019·Current Neurology and Neuroscience Reports·Amir Shaban, Enrique C Leira
Jan 18, 2020·BMJ Case Reports·Soujanya SodavarapuJeffrey Hoffman
Apr 26, 2019·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Flávia Patrícia Sena Teixeira SantosHumberto Correa
Oct 28, 2019·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Simone FargettiEduardo F Borba

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Methods Mentioned

BETA
biopsy

Software Mentioned

SPSS

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