Peripheral Th-17 cells in allergic rhinitis: New evidence

International Immunopharmacology
Giorgio CiprandiDaniela Fenoglio

Abstract

Th17 is a subset of T helper lymphocytes exerting inflammatory activities. Recently, it has been reported that serum IL-17 levels are high in patients with severe birch allergy. It was to compare the cytokine profile and the frequency of peripheral allergen-specific T helper producing IL-17 in patients with allergic rhinitis. Twelve patients with persistent allergic rhinitis due to pollens and 5 healthy non-allergic subjects were evaluated during the pollen season. Th17 were evaluated by intracellular staining in T cell compartment ex-vivo and after short activation by allergens and control antigens. Ex-vivo PBMNC evaluation showed that allergic patients had higher frequencies of IL-17 producing T cells. Functional analysis after antigen-specific CD4+ T cell expansion demonstrated that allergic patients had higher frequencies of IL-17 producing T cells than normal subjects. This preliminary study contributes to the knowledge concerning the possible role of Th-17 cells in the response to allergens.

References

Dec 24, 2002·American Journal of Respiratory Cell and Molecular Biology·Peter W HellingsJan L Ceuppens
May 20, 2005·American Journal of Respiratory Cell and Molecular Biology·Svetlana SergejevaAnders Lindén
Aug 13, 2005·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Giorgio CiprandiFrancesco Puppo
May 23, 2006·Nature Immunology·Robert L Coffman
Nov 15, 2006·The Journal of Experimental Medicine·Silvia Schnyder-CandrianBruno Schnyder
Aug 2, 2007·The Journal of Allergy and Clinical Immunology·Carsten B Schmidt-WeberCezmi A Akdis
Sep 22, 2007·Allergy and Asthma Proceedings·Christine KlemensMatthias F Kramer
Apr 23, 2008·Allergology International : Official Journal of the Japanese Society of Allergology·Keisuke ObokiSusumu Nakae
Jul 8, 2008·The Journal of Allergy and Clinical Immunology·Giorgio CiprandiGilberto Filaci
Oct 4, 2008·Current Opinion in Immunology·Yui-Hsi Wang, Yong-Jun Liu

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Citations

Jan 25, 2011·Internal and Emergency Medicine·Giuseppe MurdacaFrancesco Puppo
Dec 21, 2010·Current Allergy and Asthma Reports·Yves LaumonnierJörg Köhl
Sep 28, 2010·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Giorgio CiprandiDaniela Fenoglio
Feb 25, 2014·Journal of Animal Science and Biotechnology·Peng SunSheng-Guo Zhao
Sep 5, 2014·Immunotherapy·Caterina CuppariCarmelo Salpietro
Jul 31, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M WangC Bachert
Aug 29, 2012·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G CiprandiC Salpietro
Oct 29, 2013·International Immunopharmacology·Ieva BajoriunieneRaimundas Sakalauskas
May 23, 2015·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Fabio L M RicciardoloGiorgio Ciprandi
Mar 17, 2015·The Journal of Allergy and Clinical Immunology·Luis Diego ArchilaWilliam W Kwok
Feb 2, 2011·The Journal of Allergy and Clinical Immunology·Mohan S MaddurJagadeesh Bayry
Nov 2, 2016·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Agata SchrammTomasz P Mikolajczyk
Oct 30, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Sihai Wu, Dajiang Xiao
Jan 11, 2011·Allergy, Asthma & Immunology Research·Tunc AkkocCezmi A Akdis
Dec 18, 2012·Current Opinion in Otolaryngology & Head and Neck Surgery·Harsha H Kariyawasam, Giuseppina Rotiroti
Aug 22, 2018·Oncology Letters·Qiping ShiHaiying Jia
Jun 18, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Jonathan P HuberJ David Farrar
Nov 24, 2020·Frontiers in Immunology·Xiaofeng YuZhiwei Cao
Apr 18, 2018·International Immunopharmacology·Shenhong QuBaiwen Chen
Apr 22, 2021·Journal of Asthma and Allergy·Jun YangShengjun Wang
Jan 15, 2011·Current Opinion in Otolaryngology & Head and Neck Surgery

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