Peripheral vascular disease as a predictor of survival after coronary artery bypass grafting: comparison with a matched general population

The Annals of Thoracic Surgery
Albert H M van StratenAndré A J van Zundert

Abstract

The European system for cardiac operative risk evaluation, the most popular European scoring system in cardiac surgery, uses the extracardiac arteriopathy as a risk factor for early mortality. We studied the effect of peripheral vascular disease (PVD) on early and late mortality in a large group of patients undergoing isolated coronary artery bypass surgery (CABG) surgery. During a ten-year period (January 1998 through December 2007) 10,626 patients underwent isolated CABG in our hospital. The primary endpoints of this study were early and late all-cause mortality. For each year of the study period, general population cohorts were matched with the patient groups for age and gender (expected survival). Out of 10,504 patients included in the analysis, 1,222 (11.63%) patients had PVD. The PVD was identified as an independent risk factor for late mortality (death at any time after hospital discharge) (hazard ratio of 1.67 [1.43 to 1.95], p < 0.0001), but not for early mortality (death within 30 days or before discharge) (hazard ratio of 1.06 [0.70 to 1.60], p = 0.776). Patients without PVD had a better survival than patients with PVD (log-rank p < 0.0001) and even a better survival compared to the normal Dutch population survival (...Continue Reading

References

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Citations

Jan 24, 2014·General Thoracic and Cardiovascular Surgery·Taro NakatsuRyuzo Sakata
Dec 24, 2013·The Annals of Thoracic Surgery·Ralf E HarskampRenato D Lopes
Jan 2, 2015·Dose-response : a Publication of International Hormesis Society·Peter Whittaker, Karin Przyklenk
Jun 22, 2012·Asian Cardiovascular & Thoracic Annals·Nizar AlWaqfiKhaled Ibrahim
May 14, 2017·Circulation. Cardiovascular Quality and Outcomes·Kasper AdelborgHenrik Toft Sørensen
Sep 20, 2019·Journal of Cardiac Surgery·Massimo BonacchiSandro Gelsomino
Mar 23, 2017·Interactive Cardiovascular and Thoracic Surgery·Dmitry PevniNahum Nesher
Mar 14, 2020·Heart, Lung & Circulation·Massimo BonacchiSandro Gelsomino

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