Peripheral Vasculitic Neuropathy Associated With Minocycline Use

Journal of Clinical Neuromuscular Disease
Min K KangJayashri Srinivasan

Abstract

We describe 2 patients presenting with multiplex mononeuritis, associated with skin manifestation, secondary to minocycline-induced vasculitis. One of the cases is associated neither with lupus nor polyarteritis nodosa. An extensive laboratory workup ruled out any possible underlying immunologic disorder. Electrodiagnostic studies were conducted to show axonal neuropathy in patchy and multifocal distribution consistent with multiplex mononeuritis. This diagnosis was confirmed with nerve biopsy. Withdrawing from the offending medication, minocycline, improved the patients' clinical condition and the quantitative serological measures.

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Citations

Aug 7, 2018·Current Opinion in Neurology·Claudia Sommer

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