Peritoneal carcinomatosis: intraoperative parameters in open (coliseum) versus closed abdomen HIPEC

International Journal of Surgical Oncology
E HalkiaJ Spiliotis

Abstract

Peritoneal carcinomatosis (PC) is associated with a poor prognosis. Cytoreductive surgery (CRS) and HIPEC play an important role in well-selected patients with PC. The aim of the study is to present the differences in the intraoperative parameters in patients who received HIPEC in two different manners, open versus closed abdomen. The population includes 105 patients with peritoneal carcinomatosis from colorectal, gastric, and ovarian cancer, sarcoma, mesothelioma, and pseudomyxoma peritonei. Group A (n = 60) received HIPEC using the open technique and Group B (n = 45) received HIPEC with the closed technique. The main end points were morbidity, mortality, and overall hospital stay. There were two postoperative deaths (3.3%) in the open group versus no deaths in the closed group. Twenty-two patients in the open group (55%) had grade III-IV complications versus 18 patients in the closed group (40%). There are more stable intraoperative conditions in the closed abdomen HIPEC in CVP, pulse rate, and systolic pressure parameters. Both methods are equal in the HIPEC procedures. Perhaps the closed method is the method of choice for frail patients due to more stable hemodynamic parameters.

References

Aug 30, 2008·Journal of Surgical Oncology·Olivier GlehenGilly Francois Noel
Dec 17, 2010·World Journal of Gastrointestinal Oncology·Santiago González-MorenoGloria Ortega-Pérez
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Citations

Apr 12, 2016·Indian Journal of Surgical Oncology·S J ValleD L Morris
Jan 16, 2019·Cancers·Roxan F C P A HeldermanJohannes Crezee
May 9, 2019·Gastroenterology Research and Practice·Foteini Stefania KoumpaReza Mirnezami
Jan 26, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Daan R LökeH Petra Kok

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