Peritoneal dialysis-associated peritonitis: clinical features and predictors of outcome

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Diamantis P KofteridisGeorge Samonis

Abstract

The objective of this study was to identify the epidemiological, clinical, and microbiological factors affecting the outcome of peritoneal dialysis (PD)-associated peritonitis. All patients with PD-associated peritonitis, cared for at the University Hospital of Heraklion from 1990 to 2007, were retrospectively studied. A total of 247 episodes of PD-associated peritonitis occurring in 82 patients were evaluated. The median age of patients was 68 years (range 10-92 years); 51 (62%) were males. There were 104 episodes (42%) of Gram-positive peritonitis, 46 (19%) of Gram-negative peritonitis, 13 (5%) of polymicrobial peritonitis, and 11 (4%) of fungal peritonitis. There were 64 (26%) complicated episodes. The latter included 22 (8.9%) relapses, 13 (5.3%) repeated episodes, 18 (7.3%) catheter removals, and 11 (4.5%) deaths. In multivariate analysis, the presence of a purulent exit-site infection (p<0.001), peritoneal dialysis effluent cell count >100 x 10(6)/l for more than 5 days (p<0.001), use of antimicrobials during the preceding 3 months (p<0.05), and low serum total protein level on admission (p<0.05) were independent predictors of a complicated course. Exit-site infection, more than 5 days with a peritoneal dialysis effluent ...Continue Reading

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Citations

May 28, 2013·BMC Nephrology·Chia-Ter ChaoJenq-Wen Huang
Jun 30, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Anouk T N van DiepenSarbjit V Jassal
Aug 4, 2012·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Rong XuJie Dong
May 11, 2012·International Journal of Hygiene and Environmental Health·Patricia M SolMichiel F Schreuder
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Jul 31, 2013·Journal of Pediatric Surgery·Matthew L StoneBartholomew J Kane
Dec 17, 2015·Journal of Investigative Medicine High Impact Case Reports·Elvira O GosmanovaKerry O Cleveland
Aug 2, 2018·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Mulalo NepfumbadaRajendra Bhimma
Dec 18, 2013·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Anouk T N van Diepen, Sarbjit V Jassal
Jun 5, 2013·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Rong XuJie Dong
May 26, 2020·Kidney Research and Clinical Practice·Tae Yeon HwangJihyun Yang
Jan 4, 2019·International Urology and Nephrology·Monika Lichodziejewska-NiemierkoMarek Bronk
Jul 29, 2020·Indian Journal of Medical Microbiology·Girisha PindiSasikala Garikaparthi
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Feb 17, 2021·Indian Journal of Medical Microbiology·Girisha PindiSasikala Garikaparthi

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