Peritoneal membrane evaluation in routine clinical practice

Blood Purification
Anabela RodriguesR T Krediet

Abstract

Establishment of reference values for small solute transport, sodium sieving and effluent CA125 with 3.86% (4 h) peritoneal equilibration test (PET), and comparison with fast-fast PET with regard to small solute transport categories. Cross-sectional study; 69 prevalent patients. Sodium sieving corrected for sodium diffusion with a formula applicable to the PET. CA125 appearance rate (AR) was measured. Expected and observed 60 min D/P(creatinine) were compared by Bland and Altman. Means (95% CI): D/P(creatinine) 0.73 (0.70-0.76), MTAC(creatinine) 9.6 (8.4-10.9) ml/min, D/D0 glucose 0.30 (0.28-0.31), corrected dip 0.17 (0.15-0.18), CA125 150 (125-176) U/min. Both corrected and uncorrected sodium sieving were informative. Peritoneal transport was faster at 60 min dwell. UFF patients presented very low corrected dip and CA125 AR. 3.86% (4 h) PET provided results similar to those from SPA. Correction for diffusion of sodium sieving is dispensable for simple clinical evaluations. D/P(creatinine) at 60 min overestimated small solute transport rate. Effluent CA125 was consistently lower in UFF patients.

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Feb 8, 2007·American Journal of Nephrology·Anabela S RodriguesRaymond T Krediet

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Citations

Jul 3, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ana Marta GomesTeresa García Falcón
Mar 3, 2012·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Ana Paula BernardoAnabela Rodrigues
Mar 1, 2012·Journal of Renal Care·Rumeyza KazancioğluHuseyin Celik

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