PMID: 2102724May 1, 1990Paper

Peritoneal mesothelioma: the importance of ultrastructural study. A report of 2 cases and a review of the Spanish literature

Anales de medicina interna : organo oficial de la Sociedad Española de Medicina Interna
V M Gutiérrez-Rave PeceroE Pujol de la Llave

Abstract

Two cases of peritoneal mesothelioma (PM), with ultrastructural study, of females who lived in a rural area without asbestos exposition history are described and the Spanish literature reviewed. We highlight the association with severe autoimmune hemolytic anemia, due to the presence of cold agglutinins, in one patient without relationship to drugs or concomitant diseases. We focus on the need for thorough and multiple biopsies through laparoscopy to avoid false negative. We believe that there are no totally specific morphological data on mesothelioma, which means that the initial study is based on optical microscopy performed with hematoxylin-eosin and PAS-diastase stain using the electronic microscopy to confirm the diagnosis.

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