Perivascular epithelioid cell tumor of the liver coexisting with a gastrointestinal stromal tumor.

World Journal of Gastroenterology : WJG
Carlos Eduardo PaivaSilvia Regina Rogatto

Abstract

Approximately 10% of patients with gastrointestinal stromal tumors (GIST) develop other neoplasms, either synchronously or metachronously. In this report we describe coexistence of a gastrointestinal stromal tumor and a hepatic perivascular epithelioid cell tumor (PEComa) in a 51-year-old woman with no evidence of tuberous sclerosis. A subcapsular hepatic nodule (0.8 cm in diameter) was found during surgery for symptomatic gastric neoplasm (15 cm in diameter) arising from the lesser curvature. Both tumors revealed histomorphological and immunohistochemical features confirming a diagnosis of a small incidental hepatic PEComa and a high risky extramural gastric GIST, respectively. The patient remained disease-free 25 mo after surgery with no evidence of tumor recurrence or new neoplasms. To our knowledge, this is the first report of PEComa in a patient with GIST. Hepatic lesions detected synchronously or metachronously in patients with GISTs may represent histogenetically distinct lesions and should be sampled to confirm or exclude metastatic GISTs.

References

Mar 1, 1992·The American Journal of Surgical Pathology·F BonettiG Zamboni
Oct 1, 1984·The American Journal of Surgical Pathology·Z D Goodman, K G Ishak
Jan 15, 1999·The American Journal of Surgical Pathology·W M TsuiA P Dhillon
Apr 27, 2000·Archives of Pathology & Laboratory Medicine·A MaioranaR Adriana Fano
May 3, 2000·Histopathology·S YamasakiK Suda
Mar 27, 2002·The American Journal of Surgical Pathology·Hala R MakhloufKamal G Ishak
Apr 2, 2004·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Masaharu Fukunaga
Jun 10, 2004·World Journal of Gastroenterology : WJG·Oswens-S LoSheung-Tat Fan
Jun 30, 2004·The American Journal of Surgical Pathology·Fabiola MedeirosChristopher D M Fletcher
Aug 24, 2004·Virchows Archiv : an International Journal of Pathology·Michal MichalSaul Suster
Dec 20, 2005·Histopathology·J L Hornick, C D M Fletcher
Feb 21, 2006·World Journal of Gastroenterology : WJG·Radoslaw JaworskiGrazyna Kobierska-Gulida
May 25, 2006·Current Opinion in Oncology·Jonathan C Trent, Robert S Benjamin
Aug 2, 2006·Archives of Pathology & Laboratory Medicine·Jeremy R ParfittBret M Wehrli
Sep 19, 2006·World Journal of Gastroenterology : WJG·Marek WronskiIreneusz W Krasnodebski
Dec 30, 2006·Seminars in Diagnostic Pathology·Abbas AgaimyMarkku Miettinen

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Citations

Sep 29, 2009·Surgery Today·Janusz M StrzelczykStanislaw Sporny
May 22, 2008·World Journal of Gastroenterology : WJG·Unne Stenram
Jan 3, 2015·Asian Journal of Surgery·Zhen LiuBaosheng Wang
Mar 7, 2009·Cirugía española·Belinda Sánchez PérezJulio Santoyo Santoyo
Feb 3, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Ying-Jiang YeShan Wang
Feb 4, 2014·Case Reports in Medicine·Faseeh KhajaShanedelle Norford
Jul 7, 2015·Annals of Diagnostic Pathology·Khin Thway, Cyril Fisher
Jun 1, 2015·International Journal of Surgery Case Reports·H Ferreira E MoraJ Costa Maia
Jul 19, 2014·Diagnostic Pathology·Hassania AmeurtesseAfaf Amarti
Aug 23, 2019·World Journal of Gastroenterology : WJG·Johanna WaidhauserBruno Märkl
May 9, 2015·World Journal of Gastroenterology : WJG·Toshiya MaebayashiMasahiko Sugitani

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