PMID: 8599436Jun 1, 1995Paper

Perivascular spaces in eccrine spiradenoma. A clue to its histological diagnosis

The American Journal of Dermatopathology
J J van den Oord, C De Wolf-Peeters

Abstract

Perivascular spaces were found to represent a useful histological clue to the diagnosis of eccrine spiradenoma. They were observed in eight of nine eccrine spiradenomas but not in syringomas, nodular basal cell carcinomas, or glomangiomas. Perivascular spaces in spiradenomas consisted of variably sized spaces around one or more central blood vessels, bordered at the periphery by a palisade of tumor cells and lined at both sides by basement membrane collagen type IV. Perivascular spaces contained variable numbers of T lymphocytes in all cases and could undergo fibrosis, cystic dilatation, or hyalinization. In analogy to similar structures in thymomas, we suggest that perivascular spaces in spiradenomas are involved in the traffic of lymphocytes toward the tumor.

Citations

Aug 10, 2001·Journal of the European Academy of Dermatology and Venereology : JEADV·S GuptaB Kumar
Apr 1, 1996·The American Journal of Dermatopathology·J Rosai
Oct 3, 2002·The American Journal of Dermatopathology·Jennie ClarkeKlaus F Helm
Nov 7, 2008·International Journal of Dermatology·Zhifang ZhaiBaiyu Zhong
Jul 24, 2008·Journal of Cutaneous Pathology·Georgia LevidouAthina Androulaki

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Basal Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Basement Membranes

Basement membranes are thin, specialized extracellular matrices surrounding most tissues in all metazoans. Here is the latest research on basement membranes.

Related Papers

Virchows Archiv : an International Journal of Pathology
M Rodríguez-JustoC Santonja
The American Journal of Surgical Pathology
N HirutaM Miura
British Medical Journal
J S Lumley, A G Stansfeld
© 2021 Meta ULC. All rights reserved