PMID: 15241236Jul 9, 2004Paper

Permanent gentamicin vestibulotoxicity

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
F O BlackValerie Stallings

Abstract

To determine the natural history of permanent gentamicin vestibulotoxicity. Retrospective; comparison of retrospective and prospective studies. Tertiary neurotology clinic. Clinical research and technology center. Thirty-three subjects with permanent gentamicin-induced vestibulotoxicity. Medical records review, neurotologic examination, and vestibular and auditory function tests. Vestibular and auditory function test results at least 1 year after discontinuation of gentamicin, clinical examination results, serum gentamicin levels, and serum creatinine levels. Thirty-three subjects had vestibular function test results consistent with permanent gentamicin ototoxicity. All complained of dysequilibrium, 32 described oscillopsia, and 23 had tinnitus. All 33 subjects had complained of symptoms consistent with ototoxicity within 1 to 3 weeks of initiation of gentamicin therapy; however, gentamicin vestibulotoxicity was not recognized before hospital discharge in 32 of 33 subjects. Serum peak and trough gentamicin levels did not correlate with the development of vestibulotoxicity, nor did observance of recommended "safe" dosage ranges. Of 17 subjects whose serum creatinine levels were recorded, 6 experienced abnormal elevations in seru...Continue Reading

References

Sep 1, 1978·Acta Oto-laryngologica·O WinkelK Rozarth
May 1, 1987·The Laryngoscope·F O BlackS M Elardo
Oct 1, 1980·The Laryngoscope·W E Fee
Sep 1, 1995·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·D SaadatH Kitano
Feb 1, 1995·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·R RazS Romano
Feb 1, 1995·The Journal of Antimicrobial Chemotherapy·K ElhananR Raz
Jan 1, 1995·Archives of Otolaryngology--head & Neck Surgery·R H MargolisS E Levine
Jun 1, 1994·The Annals of Pharmacotherapy·R D Bates, M C Nahata
Apr 1, 1993·British Journal of Audiology·R ProbstR Hauser
Apr 1, 1996·The Journal of Antimicrobial Chemotherapy·W J MunckhofJ D Turnidge
May 21, 1998·Lancet·F El BakriA S Duncombe
Sep 3, 1998·Acta Oto-laryngologica·J A Waterston, G M Halmagyi
Sep 25, 2001·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·F O BlackS C Pesznecker

❮ Previous
Next ❯

Citations

Jan 25, 2006·Experimental Brain Research·Hamish G MacDougallF Owen Black
Jun 19, 2013·Experimental Brain Research·Christopher PhillipsJay T Rubinstein
Aug 13, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Scott J SchurmanThomas R Welch
Jan 29, 2013·Journal of the Association for Research in Otolaryngology : JARO·Natan S DavidovicsCharles C Della Santina
Nov 9, 2010·The Journal of Laryngology and Otology·R C DemarcoM A Hyppolito
Aug 30, 2005·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Hamish G MacDougall, Steven T Moore
Aug 17, 2011·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Rebekah M AhmedG Michael Halmagyi
Sep 8, 2007·Current Opinion in Otolaryngology & Head and Neck Surgery·Mark Douglas Rizzi, Keiko Hirose
Jun 20, 2012·Seminars in Dialysis·Leonid FeldmanJoshua Weissgarten
Oct 27, 2006·Antimicrobial Agents and Chemotherapy·Joshua D Nosanchuk, Arturo Casadevall
May 26, 2006·Antimicrobial Agents and Chemotherapy·Clement MugabeAbdelwahab Omri
Apr 7, 2007·Pediatric Research·Suvi ViskariTurkka Kirjavainen
Jun 28, 2014·Advances in Chronic Kidney Disease·Laura Troidle
Aug 13, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Chun Jie TianYun-Hoon Choung
Dec 18, 2013·Neurotoxicology·Lara Sedó-CabezónJordi Llorens
Oct 16, 2014·The Journal of Laryngology and Otology·G van KerckhovenJ A De Ru
Jul 16, 2005·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Giulia BertinoEugenio Mira
May 14, 2010·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·O A SomefunA A Abdul Azeez
Apr 14, 2006·Expert Opinion on Drug Safety·Joshua G YorgasonFederico Kalinec
Oct 7, 2015·Journal of the Association for Research in Otolaryngology : JARO·Christopher PhillipsJames O Phillips
Jul 24, 2012·Medical Hypotheses·P F Smith
Jul 30, 2015·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Yevgeniy R SemenovYuri Agrawal
Nov 19, 2011·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Sander CroesCees Neef
Oct 26, 2011·Toxicology and Applied Pharmacology·G VignauxS Besnard
Aug 26, 2010·The Medical Clinics of North America·Joe Walter Kutz
Sep 4, 2010·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Natan S DavidovicsCharles C Della Santina
Jul 4, 2006·Advances in Chronic Kidney Disease·Amy Barton Pai, Manjunath P Pai
Apr 19, 2015·Journal of Neurology, Neurosurgery, and Psychiatry·Robin T BigelowYuri Agrawal
Jul 31, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Ismail KocyigitBulent Tokgoz
Dec 29, 2012·Scandinavian Journal of Infectious Diseases·Håkan HanbergerUNKNOWN Swedish Reference Group for Antibiotics
Jul 16, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Alexander A TarnutzerKonrad P Weber
Nov 12, 2016·Auris, Nasus, Larynx·Olusola Ayodele SogebiTaiwo Olugbemiga Adedeji
Feb 17, 2017·The Journal of Laryngology and Otology·L BurrowsM Billing
Jan 12, 2017·Journal of Neurology·Pauline PoppMarianne Dieterich
Jan 21, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·David D PothierJohn A Rutka
Jul 24, 2008·The Annals of Pharmacotherapy·Robert E ArianoDiamond A Kassum
Jul 25, 2017·Pediatric Pulmonology·Jaynee A HandelsmanWilliam M King
Feb 7, 2018·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Kathleen C M Campbell, Colleen G Le Prell
May 10, 2018·International Journal of Audiology·Jaynee A Handelsman
Aug 5, 2017·The Laryngoscope·Allison K IkedaJennifer J Shin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Related Papers

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Rebekah M AhmedG M Halmagyi
Journal of Neurology, Neurosurgery, and Psychiatry
K Jáuregui-RenaudAdolfo Bronstein
Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
F O BlackS C Pesznecker
© 2022 Meta ULC. All rights reserved