Permanent implantation of iodine-125 seeds as a salvage therapy for recurrent head and neck carcinoma after radiotherapy

Cancer Investigation
Na MengRui Jie Yang

Abstract

Seventeen patients with head and neck recurrent carcinoma underwent (125)I seed implantation under CT or ultrasound guidance. The actuarial D90 of the (125)I seeds implanted was 90-160 Gy (median, 126 Gy). Median follow-up was 10 months (range, 3-48 months). The median local control time was 16 months; the 1- and 2-year local control rates were 66.5% and 49.9%, respectively. The 1- and 2-year survival rates were 51.3% and 38.5%, respectively (median, 16 months). None of the patients experienced grade 4 toxicity. (125)I seed implantation was a feasible and effective salvage treatment for patients with recurrent head and neck cancers.

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Citations

Mar 20, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Hongwu WangSujuan Liang
Oct 3, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Xin GeJian-Min Ma
Feb 11, 2015·World Journal of Gastroenterology : WJG·Fei WeiMasataka Murakami
Jul 22, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Sheng PengFu-Jun Zhang
Jan 23, 2019·Pediatric Blood & Cancer·Peng ChenJian-Guo Zhang
Jul 19, 2017·ACS Applied Materials & Interfaces·Yahui YangTianfeng Chen

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