Permanent pacemaker implantation after pediatric heart transplantation: Risk factors, indications, and outcomes

Clinical Transplantation
Adil MahmoodJacob Simmonds

Abstract

Permanent pacemaker (PPM) placement in adults following orthotopic heart transplantation (OHT) has been well documented. However, studies concerning the need for PPM implantation in pediatric heart transplant recipients are less common. Institutional transplant and pacing databases as well as patient medical records were reviewed for all pediatric patients undergoing OHT (n = 314; all with bicaval connection) at our institution between January 2000 and March 2018. A total of 16 patients (5.1%) were implanted with a pacemaker after transplantation. Donor age was the only significant risk factor for post-transplant PPM implantation, with a median age of 28.5 years (7.0-49.0) in the pacing group vs 15.5 years (0.4-56.0) in the non-pacing group (P = 0.009). Indication for pacemaker insertion was more often complete heart block (CHB) (12/16, 75%) than sinus node dysfunction (SND) (4/16, 25%). There was no significant difference in mortality between recipients who received a PPM and those who did not (log-rank test; P = 0.345). Increasing donor age is associated with increased PPM placement following pediatric heart transplantation. Interestingly, a high proportion of CHB patients recovered sinus rhythm, and long-term outcomes for pa...Continue Reading

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Citations

Aug 2, 2021·Indian Pacing and Electrophysiology Journal·UNKNOWN Writing Committee MembersUNKNOWN Document Reviewers
Aug 8, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·UNKNOWN Writing Committee MembersPhilip L Wackel
Aug 3, 2021·Cardiology in the Young·Maully J ShahUNKNOWN Document Reviewers: Philip M. Chang, Fabrizio Drago, Anne M. Dubin, Susan P. Etheridge, Apichai Kongpatanayothin, Jose Manue

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