Permeability and Weibel-Palade Bodies of the Blood Vessels in the Human Vocal Fold Mucosa

The Laryngoscope
Kiminori SatoHirohito Umeno

Abstract

Transendothelial exchange and permeability of the capillaries in Reinke space (the superficial layer of the lamina propria) of the vocal fold mucosa affect physiological and pathological conditions of the human vocal fold mucosa. The mechanism of permeability and Weibel-Palade bodies of the blood vessels in the human vocal fold mucosa were investigated using electron microscopy. Histologic analysis of the human vocal fold. Six normal human vocal folds (three adults and three newborns) obtained from autopsy cases and three human vocal folds with Reinke edema from surgical specimens were investigated under transmission electron microscopy. There were three possible capillary wall transport systems related to the permeability of the blood vessels in the vocal fold mucosa: 1) Fenestra transport, plasma exuded from the capillaries into surrounding tissue via the fenestration with or without a diaphragm; 2) vesicular transport (transcellular transport via vesicles), the use of vesicles to ferry fluid and solutes across endothelial cells; and 3) junctional transport (intercellular transport), molecules passed through intercellular gaps between endothelial cells. Weibel-Palade bodies were present in the cytoplasm of endothelial cells b...Continue Reading

References

Jan 1, 1982·Archives of Oto-rhino-laryngology·H Frenzel, O Kleinsasser
Jun 1, 1997·The Annals of Otology, Rhinology, and Laryngology·K Sato, M Hirano
Oct 1, 1964·The Journal of Cell Biology·E R WEIBEL, G E PALADE
Dec 1, 1961·The Journal of Biophysical and Biochemical Cytology·G MAJNOG I SCHOEFL
Feb 14, 2006·Arteriosclerosis, Thrombosis, and Vascular Biology·Mariska G RondaijJan Voorberg
May 22, 2010·Journal of Voice : Official Journal of the Voice Foundation·Désirée Louise DrägerLucian Sulica
Jan 27, 2011·Blood·Karine M ValentijnJeroen Eikenboom

❮ Previous
Next ❯

Citations

Feb 20, 2021·The Laryngoscope·Christine Murphy EstesLucian Sulica

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Annals of Otology, Rhinology, and Laryngology
K SatoT Nakashima
The Laryngoscope
Flavio Akira SakaeDomingos Hiroshi Tsuji
The Annals of Otology, Rhinology, and Laryngology
Flavio Akira SakaePaulo Hilário N Saldiva
Ear, Nose, & Throat Journal
Eliana VergheseRobert T Sataloff
© 2022 Meta ULC. All rights reserved