Pernicious anemia presenting as catatonia: correlating vitamin B12 levels and catatonic symptoms

General Hospital Psychiatry
Damien BramGuillaume Vaiva

Abstract

Pernicious anemia has been associated with various psychiatric manifestations, such as depression, mania and psychosis. Psychiatric symptoms can sometimes occur without hematological and neurological abnormalities and can be prodromal of vitamin B12 deficiency. We report a case of autoimmune B12 deficiency presenting as catatonia without signs of anemia or macrocytosis, in which a correlation was found between the patient's B12 blood levels and catatonic symptoms over time. This catatonic episode was successfully treated with only lorazepam and adequate doses of cyanocobalamin.

References

Jun 30, 1988·The New England Journal of Medicine·J LindenbaumR H Allen
Mar 8, 1997·Lancet·P ThomasG Vaiva
Jun 26, 2003·Acta Psychiatrica Scandinavica·N BerryB M Tripathi
Aug 4, 2004·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Emmanuel AndrèsJean-Frédéric Blicklé
Sep 3, 2010·The British Journal of Psychiatry : the Journal of Mental Science·Sameer JauharPeter J McKenna
Mar 28, 2012·The Journal of Neuropsychiatry and Clinical Neurosciences·Christian LachnerWilliam T Regenold
May 1, 2012·The Journal of Emergency Medicine·Katherine E KrollCarrie D Tibbles

❮ Previous
Next ❯

Citations

May 17, 2019·Terapevticheskiĭ arkhiv·Ch S PavlovE A Andreev
Apr 12, 2017·Journal of Child and Adolescent Psychopharmacology·Neera GhaziuddinDirk M Dhossche

❮ Previous
Next ❯

Related Concepts

Related Feeds

Catatonia

Catatonia is a psychomotor syndrome with motor and behavioral symptoms, and can occur in both patients with or without psychiatric illness. Discover the latest research on Catatonia here.

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Catatonic Schizophrenia

Catatonia is a psychomotor symptom in which patients present with stupor, although catatonic excitement may also present at the other end of the spectrum. Catatonia has been historically associated with schizophrenia although it is also associated with other neuropsychiatric disorders. Find the latest research on catatonic schizophrenia here.

Related Papers

The British Journal of Psychiatry : the Journal of Mental Science
Sameer JauharPeter J McKenna
The Southeast Asian Journal of Tropical Medicine and Public Health
S InsiripongS Areekul
La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
R WOLFF, F BESANCON
General Hospital Psychiatry
Naren P RaoRavi S Pandey
© 2021 Meta ULC. All rights reserved