Peroxisomes and Innate Immunity: Antiviral Response and Beyond

International Journal of Molecular Sciences
Ana Rita FerreiraDaniela Ribeiro

Abstract

Peroxisomes are ubiquitous organelles with well-defined functions in lipid and reactive oxygen species metabolism, having a significant impact on a large number of important diseases. Growing evidence points to them, in concert with mitochondria, as important players within the antiviral response. In this review we summarize and discuss the recent findings concerning the relevance of peroxisomes within innate immunity. We not only emphasize their importance as platforms for cellular antiviral signaling but also review the current information concerning their role in the control of bacterial infections. We furthermore review the recent data that pinpoints peroxisomes as regulators of inflammatory processes.

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Citations

Jul 7, 2020·International Journal of Molecular Medicine·Felician StancioiuAristidis Tsatsakis
Mar 7, 2021·Antioxidants·Marc Herb, Michael Schramm
Jun 11, 2021·Life Science Alliance·Onruedee KhantisitthipornMichael R Beard
Aug 8, 2021·International Journal of Molecular Sciences·Malin Tordis MeyerSrikanth Karnati
Aug 6, 2021·Antioxidants & Redox Signaling·Arjun SharmaMarkus Bosmann
Nov 23, 2021·Frontiers in Genetics·Amelie S Lotz-HavlaSøren W Gersting

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