Persistence lengths and structure factors of wormlike polymers under confinement

The Journal of Physical Chemistry. B
Peter CifraTomás Bleha

Abstract

The behavior of semiflexible chains modeling wormlike polymers such as DNA and actin in confined spaces was explored by coarse-grained Monte Carlo simulations. The persistence length P, mean end-to-end distance R2, mean radius of gyration Rg2, and the size ratio R2/Rg2 were computed for chains in slits, cylinders, and spheres. It was found that the intrinsic persistence length of a free chain undergoes on confinement substantial alteration into the apparent persistence length. The qualitative differences were found in trends of the apparent persistence lengths between slits and cylinders on one side and spheres on the other side. The quantities P, R2, Rg2, and R2/Rg2 display similar dependences upon squeezing the chains in nanopores. The above quantities change nonmonotonically with confinement in slits and cylinders, whereas they drop smoothly with decreasing radius of a sphere. For elongation of a chain in a cylinder, two regimes corresponding to strong and moderate confinements were found and compared to experiments and predictions of the blob and Odijk theories. In a spherical cavity, the toroidal chain structure with a hole in the center was detected under strong confinements. The scattering form factor S(q) computed for s...Continue Reading

References

Mar 1, 1995·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·J HendricksW Zimmermann
Nov 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·J KindtW M Gelbart
Jul 15, 2004·Proceedings of the National Academy of Sciences of the United States of America·Jonas O TegenfeldtRobert H Austin
Feb 9, 2005·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Y-L ChenP S Doyle
Apr 20, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·F Brochard-WyartP-G de Gennes
Aug 11, 2005·Physical Review Letters·Walter ReisnerRobert H Austin
Sep 16, 2005·The Journal of Chemical Physics·G Morrison, D Thirumalai

❮ Previous
Next ❯

Citations

Dec 4, 2008·Faraday Discussions·Peter CifraTomás Bleha
Mar 10, 2012·The Journal of Chemical Physics·Rakwoo Chang, Kyubong Jo
Dec 25, 2015·Soft Matter·Sina Mirzaeifard, Steven M Abel
Nov 25, 2014·Biophysical Journal·Sanjin Marion, Antonio Siber
Jun 23, 2015·Journal of Computational Chemistry·Sandra C C NunesAlberto A C C Pais
Jul 1, 2010·Physical Chemistry Chemical Physics : PCCP·Peter CifraTomás Bleha
Oct 19, 2017·Scientific Reports·Fernando Vargas-LaraJack F Douglas
Apr 15, 2016·Polymers·Zhaoyang WeiJianguo Mi
Apr 3, 2012·Physical Review Letters·Bernd Nöding, Sarah Köster
Jul 4, 2008·The Journal of Physical Chemistry. B·Peter CifraErik Nies
Feb 10, 2009·The Journal of Physical Chemistry. B·Peter CifraTomás Bleha
Aug 13, 2017·Journal of the American Society for Mass Spectrometry·Myong In Oh, Styliani Consta

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.