Persistence of antibodies after vaccination against tick-borne encephalitis

International Journal of Medical Microbiology : IJMM
Pamela Rendi-WagnerHerwig Kollaritsch

Abstract

Active vaccination against the tick-borne encephalitis (TBE) virus has successfully been implemented in endemic countries for many years. However, little was known about persistency of antibodies after completion of the primary vaccination and/or TBE booster immunization. Five recently performed serological follow-up studies in adults have now revealed that the persistence of protective immunity following at least one booster immunization was longer than expected. Notably, studies which analyzed different age groups indicate differences between younger adults aged 18-49 years and older adults aged > or = 50 years with respect to TBE antibody persistence and the immune response following a subsequent booster dose. To summarize, the serological studies included in this analysis generally support a reconsideration of current TBE booster recommendations and a prolongation of booster intervals at least in younger adults.

Citations

Jun 13, 2012·Wiener medizinische Wochenschrift·Tomas Jelinek
Feb 3, 2016·Human Vaccines & Immunotherapeutics·Ursula WiedermannAngelika Wagner
Oct 26, 2010·Travel Medicine and Infectious Disease·Eckhardt PetriOlaf Zent
Nov 6, 2008·Travel Medicine and Infectious Disease·Angelika BanzhoffOlaf Zent
Sep 18, 2007·Vaccine·Franz X HeinzMichael Kundi
Jun 20, 2012·Journal of Medical Virology·Tatjana BaldovinVincenzo Baldo
Aug 30, 2008·Infectious Disease Clinics of North America·Reinhard Kaiser
Nov 30, 2011·Vaccine·H H AsklingL Lindquist
Feb 28, 2015·Pathogens and Disease·Maria Elena RemoliMaria Grazia Ciufolini
Apr 24, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J N WagnerT J von Oertzen
Aug 19, 2020·Vaccines·Mareike KubinskiGuus F Rimmelzwaan

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