Persistence of multidrug-resistant Staphylococcus haemolyticus in an animal veterinary teaching hospital clinic

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
Maan Singh SidhuHenning Sørum

Abstract

In the recent decades, coagulase-negative staphylococci (CNS) have emerged as important nosocomial pathogens with the ability to develop resistance to antibiotics and disinfectants. Multidrug-resistant CNS are currently a common finding in hospital settings and hospitalized patients. Little is known about the occurrence and persistence of multidrug-resistant CNS in animal clinics. A survey of the environmental bacterial flora in a small animal clinic showed a predominance of bacterial species commonly isolated from skin and feces of warm-blooded animals and the environment. At samplings separated by 3 years, multidrug-resistant Staphylococcus haemolyticus was isolated from the floor of four separate animal cages and from a cat's postoperative wound infection. Pulsed-field electrophoresis, multilocus enzyme typing, susceptibility testing, and genotypic characterization suggested that the multidrug-resistant S. haemolyticus isolates belonged to an epidemiological clone. All isolates harbored a chromosomal copy of the mecA gene, a 45-kb plasmid harboring the blaZ and qacA/B determinants, and all except one isolate carried multiple plasmids in the size range 1-22 kb, of which those <5 kb encoded resistance to tetracycline (tetK), m...Continue Reading

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Citations

Apr 8, 2010·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Kristin HegstadSiamak P Yazdankhah
Feb 17, 2009·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Madelaine NorströmHilde Kruse
Jun 5, 2012·Journal of the American Veterinary Medical Association·Elizabeth HamiltonCharles E DeCamp
Dec 9, 2014·Jundishapur Journal of Microbiology·Hajar MadahiFarhad Safarpoor Dehkordi
Nov 25, 2014·American Journal of Veterinary Research·Cheryl L WoodLouis G Luempert
Nov 28, 2012·The Veterinary Clinics of North America. Small Animal Practice·Christine L Cain
Nov 29, 2014·Annals of Clinical Microbiology and Antimicrobials·Modestas RuzauskasDainius Zienius
Mar 19, 2013·International Journal of Medical Microbiology : IJMM·Sarah WendlandtKristina Kadlec
Feb 10, 2021·Pathogens·Angela FrançaLuís D R Melo
Jul 12, 2018·Microbiology Spectrum·Stefan SchwarzJianzhong Shen

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