Persistence of the antibiotic sulfamethoxazole in river water alone or in the co-presence of ciprofloxacin

The Science of the Total Environment
Luisa PatroleccoAnna Barra Caracciolo

Abstract

Sulfamethoxazole and ciprofloxacin are among the most prescribed antibiotics and are frequently detected in surface water ecosystems. The aim of this study was to assess the role of a riverine natural microbial community in sulfamethoxazole (SMX) degradation in presence and absence of ciprofloxacin (CIP). River samples were collected from a stretch of the Tiber River highly impacted by human pressure. An experimental set up was performed varying some abiotic (dark/UV-light) and biotic (presence/absence of microorganisms) conditions that can affect antibiotic degradation. The residual concentrations of SMX and CIP were measured (HPLC-MS or HPLC-UV/FLD) and the effects on the natural microbial community were assessed in terms of microbial number (N. live cells/mL) and structure (Fluorescence In Situ Hybridization - FISH). Finally, the occurrence of the antibiotic resistance sul1 gene was also verified using quantitative PCR (qPCR). In 28 days, in the presence of both UV-light and microorganisms SMX disappeared (<LOD). SMX decreased partially in the dark (24%) and a slightly higher depletion was found in sterile river water and UV-light (30%). However, only in the presence of the microbial populations and in dark conditions, SMX d...Continue Reading

Citations

Oct 13, 2020·Frontiers in Microbiology·Valentina Mazzurco MiritanaAnna Barra Caracciolo
Oct 28, 2020·International Journal of Environmental Research and Public Health·Nada HannaCecilia Stålsby Lundborg
Feb 3, 2021·International Journal of Environmental Research and Public Health·Klaudia KokoszkaSylwia Bajkacz
Apr 12, 2021·The Science of the Total Environment·Pinakshi Biswas, Bhanu Prakash Vellanki
Apr 24, 2021·Chemosphere·Theresa AdesanyaAnnemieke Farenhorst
Jul 6, 2021·Water Research·Chiara BorsettoElizabeth M H Wellington

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