PMID: 6166260Jul 1, 1981Paper

Persistent bipolar illness after steroid administration

Archives of Internal Medicine
R Pies

Abstract

A 28-year-old woman received a single course of corticosteroids for treatment of ulcerative colitis. She subsequently became depressed; shortly thereafter, signs of mania developed. Despite discontinuation of corticosteroid therapy, the patient has had five bouts of mania, closely followed by severe depression, in the past 1 1/2 years. This seems to be the first case of persistent bipolar illness after exogenous steroid administration.

Citations

Feb 14, 2003·General Hospital Psychiatry·François Sirois
Jan 1, 1989·Cancer Investigation·F C StiefelJ C Holland
Feb 15, 2000·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·S B Patten, C I Neutel

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