PMID: 9440186Jan 1, 1997Paper

Persistent hyperplastic primary vitreous: diagnosis, treatment and results

Transactions of the American Ophthalmological Society
Z F Pollard

Abstract

While the great majority of patients with persistent hyperplastic primary vitreous never obtain useful vision, it is encouraging that 18.07% of all the patients in this series did achieve 20/200 vision or better (Table V). In the whole group, 12 of 83, or 14.45%, obtained 20/70 vision or better with treatment. All of these successful results were in eyes with the purely anterior PHPV only. In fact, when looking at the results of the anterior PHPV cases alone, 15 of 21 achieved 20/200 or better, which was 71.4% of the patients with anterior presentation only. In this anterior group, 12 of 21 (57.1%) attained 20/70 vision or better with treatment. The goals of treatment with PHPV should always be kept in mind when confronted with an infant who has this entity. First, an effort should be made to save the eye from glaucoma or phthisis, which are the most devastating results of untreated PHPV. A lensectomy will usually prevent the secondary glaucoma, which results from the lens-iris diaphragm being pushed forward to cause a secondary angle-closure glaucoma. A secondary glaucoma can also be produced from recurrent hyphema, which scars the outflow passageways in the angle. By removing the PHPV membrane and reducing the tractional forc...Continue Reading

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