Persistent increase of blood lead level and suppression of δ-ALAD activity in northern bobwhite quail orally dosed with even a single 2-mm spent lead shot

Archives of Environmental Contamination and Toxicology
S D HolladayR M Gogal

Abstract

Birds that display grit ingestion behavior are potentially at risk of lead (Pb) poisoning from mistaken ingestion of spent Pb shot pellets. The majority of available studies designed to assess such risk have used unspent shot pellets rather than field-obtained spent shot, which is oxidized and otherwise changed by weathering. Available studies also often administered more or heavier shot pellets to a bird than it might be expected to ingest. The current study dosed northern bobwhite quail (Colinus virginianus) weighing 194.6 ± 23.1 g (female birds) and 199.3 ± 12.2 g (male birds) with one to three spent no. 9 Pb shot collected from a skeet range, with particular interest in the toxicity that may occur from ingestion of a single 2-mm, 50 mg shot. An 8 week post-dosing clinical observation period was employed, over which feed consumption, body weight, blood Pb levels, and a battery of blood physiological parameters were made. Weight loss occurred in the birds, including male birds dosed with one Pb pellet. Erythrocyte delta aminolevulinic acid dehydratase (δ-ALAD) levels were decreased for the duration of the study across exposures and to levels associated with injury in wild bird populations. Decreased ALAD was particularly seve...Continue Reading

References

Nov 1, 1992·Bulletin of Environmental Contamination and Toxicology·W StansleyD E Roscoe
Sep 1, 1991·Biological Trace Element Research·M HiraiY Kodama
Jun 1, 1990·Environmental Health Perspectives·R A Goyer
Feb 1, 1988·Bulletin of Environmental Contamination and Toxicology·D J Pain, B A Rattner
Jan 1, 1987·Journal of Psycholinguistic Research·J M Stewart, C M Barach
Dec 1, 1986·Environmental Research·M Mautino, J U Bell
Jan 1, 1983·Archives of Environmental Contamination and Toxicology·W C EastinC T O'Leary
May 1, 1993·Archives of Environmental Contamination and Toxicology·K YamamotoY Isii
Feb 24, 2001·Environmental Pollution·N B VyasG H Heinz
Jan 20, 2005·Archives of Environmental Contamination and Toxicology·W N BeyerJ Spann
Jan 27, 2007·Journal of Wildlife Diseases·Oliver H PatteeMilton R Smith
Sep 14, 2010·Environmental Toxicology and Chemistry·Richard KerrRobert Gogal
Mar 2, 2011·Archives of Environmental Contamination and Toxicology·Richard KerrRobert Gogal
Feb 1, 1994·Environmental Monitoring and Assessment·C J HennyR A Grove

❮ Previous
Next ❯

Citations

Jun 23, 2020·The Journal of Veterinary Medical Science·Nana UshineShin-Ichi Hayama

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.