PMID: 9432161Feb 12, 1998Paper

Persistent MR contrast enhancement of calcified neurocysticercosis lesions.

AJNR. American Journal of Neuroradiology
T N ShethW Kucharczyk

Abstract

We sought to determine whether cysticercosis lesions in the brain continue to enhance after nodular involution and complete calcification, and to investigate the clinical significance of this finding with respect to seizure recurrence after cysticidal treatment. Serial contrast-enhanced MR images were obtained in all patients with neurocysticercosis seen at our hospital over a 6-year period (1991-1997). From this group, all patients with nodular calcified lesions were selected for study. Sixteen of 29 patients with neurocysticercosis had nodular calcified lesions. Six of these 16 had rim enhancement of nodular calcified lesions for at least 1 year after imaging evidence of complete calcification. Three of these six patients with enhancing, calcified lesions continued to experience seizures. Three of the 10 patients without enhancement also continued to have seizures. Contrary to the literature, which states that enhancement and disease activity cease with calcification, six (38%) of 16 patients had lesions that continued to enhance after complete calcification. This abnormality may be a risk factor for posttreatment seizures or may suggest eventual resorption of the calcified lesion.

Associated Clinical Trials

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Tropical Medicine & International Health : TM & IH
A SeckaS Geerts
Indian Journal of Medical Microbiology
S KaliaperumalS C Parija
© 2021 Meta ULC. All rights reserved