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Persistent Neuroinflammation and Brain Specific Immune Priming in A Novel Survival Model of Murine Pneumosepsis

Shock

Aug 13, 2019

Scott J DenstaedtBenjamin H Singer

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Abstract

Pneumonia is the leading cause of sepsis and septic shock. Patients who survive pneumonia are vulnerable to long-term complications including increased risk of neurocognitive dysfunction. This study investigated the immune response and long-term complications of a non-surgical mouse mod...read more

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Antibiotics
Brain
Complication
Gene Expression
Inflammation
Lipopolysaccharides
Pneumonia
Septic Shock
Spleen
Cytokine
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Persistent Neuroinflammation and Brain Specific Immune Priming in A Novel Survival Model of Murine Pneumosepsis

Shock

Aug 13, 2019

Scott J DenstaedtBenjamin H Singer

PMID: 31415473

DOI: 10.1097/shk.0000000000001435

Abstract

Pneumonia is the leading cause of sepsis and septic shock. Patients who survive pneumonia are vulnerable to long-term complications including increased risk of neurocognitive dysfunction. This study investigated the immune response and long-term complications of a non-surgical mouse mod...read more

Mentioned in this Paper

Antibiotics
Brain
Complication
Gene Expression
Inflammation

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