PERSISTENT PLACOID MACULOPATHY: A Systematic Review

Retina
Anton M Kolomeyer, Alexander J Brucker

Abstract

To review the literature on persistent placoid maculopathy. Several databases were searched for all years for "persistent placoid maculopathy." A total of 21 unique patients were identified (most commonly Caucasian men in their 50s and 60s). Mean ± SD age at time of presentation was 58.6 ± 6.9 years of age, and follow-up time was 29.2 ± 51.9 months. Thirty-three (79%) eyes had subjective symptoms on presentation. Five (24%) patients presented with a prodrome, and four (19%) patients had vitreous cell. Mean ± SD logarithm of minimal angle of resolution presenting versus final vision was 0.48 ± 0.50 (Snellen equivalent, 20/60) versus 0.63 ± 0.52 (Snellen equivalent, 20/84). Systemic inflammation and autoimmune disease were associated with worse presenting and final vision. Persistent placoid maculopathy characteristic imaging features that aid in diagnosing this rare clinical entity include the following: 1) plaque-like hypopigmented, white/yellowish foveal/perifoveal lesions on color fundus photography; 2) early hypofluorescence and late "fill-in" or staining on fluorescein angiography; 3) persistent hypocyanescence on indocyanine green angiography; and 4) choriocapillaris hyposignal on optical coherence tomography angiography. ...Continue Reading

References

Aug 7, 2007·Ophthalmology·Pamela R GolchetEdward Stroh
Jan 2, 2008·Ophthalmology·Moncef Khairallah, Salim Ben Yahia
Jul 30, 2010·Ocular Immunology and Inflammation·Maurizio Battaglia ParodiFrancesco Bandello
May 11, 2012·Journal of Ophthalmic Inflammation and Infection·Bettina C ThomasFriederike Mackensen
Dec 7, 2013·JAMA Ophthalmology·Mohamed G GendyLee M Jampol
Apr 19, 2016·Retinal Cases & Brief Reports·Nathalie PucheEric H Souied
Aug 16, 2017·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Eva LenassiNatasa Vidovič Valentinčič
Dec 19, 2017·Ophthalmic Surgery, Lasers & Imaging Retina·Thérèse M SassalosMichael D Ober

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Citations

Aug 17, 2019·Ocular Immunology and Inflammation·Pierre GasconThibaud Mathis
Sep 15, 2020·The Neurologist·Alejandra Collía FernándezJuan C García-Moncó
Dec 4, 2020·European Journal of Ophthalmology·Maria Luisa Gois da FonsêcaRaul Nunes Galvarro Vianna
Jan 21, 2021·The British Journal of Ophthalmology·Alessandro MarcheseGiuseppe Casalino
Sep 17, 2021·Journal of Ophthalmic Inflammation and Infection·Ilaria TestiCarlos Pavesio
Jul 26, 2019·Retinal Cases & Brief Reports·Matthew R StarrJose S Pulido

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