Persistent postoperative complaints after whole sural nerve biopsies in diabetic and non-diabetic subjects

Diabetic Medicine : a Journal of the British Diabetic Association
L B DahlinG Sundkvist

Abstract

The postoperative effects of a whole sural nerve biopsy in diabetic (11) and non-diabetic (10 healthy controls, 10 patients with impaired glucose tolerance and 2 patients with polyneuropathy) subjects were investigated by a mailed questionnaire 20-44 months after the surgical procedure (10/11 vs 21/22 answers received). Pain in the biopsy area at follow-up was reported in 4/10 of the diabetic patients (p = 0.01) but in none of the non-diabetic subjects (0/21). An increased number (p = 0.01) of diabetic patients (5/10 vs 1/21) had cold intolerance in their foot or leg whereas 11/31 of all patients had dysaesthesia in the affected skin. Overall 6/31 patients described serious problems at the time of the questionnaire, and 4 of this 6 having diabetes. Loss of sensation was reported in almost all subjects irrespective of diabetes or not; however, a decrease in the area of loss of sensation was reported most often in diabetic patients (8/10 vs 8/21, p = 0.02). It is concluded that whole surval nerve biopsies give rise to persistent problems both in diabetic and non-diabetic subjects. The reason for a sural nerve biopsy has always to be carefully considered before being conducted.

Citations

Mar 13, 2014·Journal of Occupational Medicine and Toxicology·Lars B DahlinAnders Björkman
Jun 7, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·David A HiltonConnie Tengah
May 27, 2004·Diabetes Care·Andrew J M BoultonJay M Sosenko
Mar 14, 2008·Acta Neurologica Scandinavica·L B DahlinG Sundkvist
Jan 22, 2009·Acta Neurologica Scandinavica·S ThrainsdottirL B Dahlin
Jan 8, 2009·Diabetic Medicine : a Journal of the British Diabetic Association·N O B ThomsenL B Dahlin
Sep 18, 2009·Muscle & Nerve·Chris A CampbellRaymond F Morgan
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Mar 1, 2006·Journal of Clinical Neuromuscular Disease·James Fallon ThorntonChristopher Jerron Riley
Jan 23, 2009·Annals of Plastic Surgery·Ivica Ducic, Justin West
Jul 31, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Peter Y K Van den BerghHaluk A Topaloglu
Jan 6, 2009·The Journal of Hand Surgery·A C J RuijsS E R Hovius

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