Abstract
The emergence of pathogens resistant to antimicrobials has prompted political initiatives targeting a reduction in the use of veterinary antimicrobials in Denmark, especially for pigs. This study elucidates the tendency of pig farms with a significantly higher antimicrobial use to remain in clusters in certain geographical regions of Denmark. Animal Daily Doses/100 pigs/day were calculated for all three age groups of pigs (weaners, finishers and sows) for each quarter during 2012-13 in 6,143 commercial indoor pig producing farms. The data were split into four time periods of six months. Repeated spatial cluster analyses were performed to identify persistent clusters, i.e. areas included in a significant cluster throughout all four time periods. Antimicrobials prescribed for weaners did not result in any persistent clusters. In contrast, antimicrobial use in finishers clustered persistently in two areas (157 farms), while those issued for sows clustered in one area (51 farms). A multivariate analysis including data on antimicrobial use for weaners, finishers and sows as three separate outcomes resulted in three persistent clusters (551 farms). Compared to farms outside the clusters during this period, weaners, finishers and sows...Continue Reading
References
Apr 30, 1995·Statistics in Medicine·M Kulldorff, N Nagarwalla
Jun 10, 1998·Preventive Veterinary Medicine·R H DunlopR M Friendship
Jul 23, 1999·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·D MaesA de Kruif
Sep 24, 1999·International Journal of Antimicrobial Agents·F M Aarestrup
May 9, 2000·Veterinary Microbiology·I H Brown
Jun 23, 2000·Veterinary Research·D MaesA de Kruif
Feb 1, 2002·Preventive Veterinary Medicine·Sten MortensenPreben Willeberg
Feb 13, 2003·Preventive Veterinary Medicine·H StegeA Thougaard
Mar 24, 2004·Veterinary Microbiology·C S KristensenS E Jorsal
Apr 7, 2004·Veterinary Microbiology·C S KristensenS E Jorsal
Aug 25, 2004·Preventive Veterinary Medicine·V F JensenF Bager
Jan 26, 2006·Statistics in Medicine·Martin KulldorffLuiz Duczmal
Aug 16, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·P C McParlandD J Taylor
Jan 12, 2007·Statistics in Medicine·Martin KulldorffRichard Platt
Mar 25, 2008·The Veterinary Record·H H PetersenJ P Nielsen
Apr 9, 2008·The Veterinary Journal·Marina SibilaJoaquim Segalés
Oct 22, 2009·International Journal of Health Geographics·Martin KulldorffKevin Konty
Nov 27, 2009·Preventive Veterinary Medicine·Håkan VigreVibeke Frøkjaer Jensen
Nov 13, 2010·Preventive Veterinary Medicine·G K HybschmannH Houe
May 14, 2011·Journal of Veterinary Pharmacology and Therapeutics·V F JensenF M Aarestrup
May 25, 2011·Journal of Animal Science·H J van der Fels-KlerxS L G E Burgers
Jan 19, 2012·Transboundary and Emerging Diseases·P BaekboL E Larsen
Apr 13, 2012·Preventive Veterinary Medicine·Bénédicte CallensJeroen Dewulf
Mar 5, 2014·Veterinary Microbiology·Lourdes Garcia-MiguraFrank M Aarestrup
Apr 15, 2015·Preventive Veterinary Medicine·Thitiwan PatanasatienkulCrawford W Revie
May 5, 2016·Acta Veterinaria Scandinavica·Nana DupontHelle Stege
Citations
Mar 18, 2017·Frontiers in Veterinary Science·Luís P CarmoIoannis Magouras
Feb 22, 2017·Epidemiology and Infection·A C BirkegårdN Toft
Jun 13, 2019·The Veterinary Record·Esben Oestergaard EriksenJohn Elmerdahl Olsen
Jun 30, 2019·BMC Veterinary Research·Cécile J M AdamMathilde C Paul